Combined GEP 70-gene and sIL-6r–level risk groups by MM molecular subgroups (N = 626)
| Molecular subgroup . | Low-risk GEP/low sIL-6r (n = 451) . | Low-risk GEP/high sIL-6r (n = 94) . | High-risk GEP/low sIL-6r (n = 46) . | High-risk GEP/high sIL-6r (n = 35) . |
|---|---|---|---|---|
| CD-1 | 31 (7) | 4 (4) | 2 (4) | 4 (11) |
| CD-2 | 80 (18) | 8 (9) | 1 (2) | 0 (0) |
| HY | 159 (35) | 28 (30) | 7 (15) | 2 (6) |
| LB | 41 (9) | 24 (26) | 1 (2) | 0 (0) |
| MF | 12 (3) | 8 (9) | 7 (15) | 9 (26) |
| MS | 55 (12) | 8 (9) | 9 (20) | 6 (17) |
| MY | 43 (10) | 7 (7) | 0 (0) | 0 (0) |
| PR | 30 (7) | 7 (7) | 19 (41) | 14 (40) |
| Molecular subgroup . | Low-risk GEP/low sIL-6r (n = 451) . | Low-risk GEP/high sIL-6r (n = 94) . | High-risk GEP/low sIL-6r (n = 46) . | High-risk GEP/high sIL-6r (n = 35) . |
|---|---|---|---|---|
| CD-1 | 31 (7) | 4 (4) | 2 (4) | 4 (11) |
| CD-2 | 80 (18) | 8 (9) | 1 (2) | 0 (0) |
| HY | 159 (35) | 28 (30) | 7 (15) | 2 (6) |
| LB | 41 (9) | 24 (26) | 1 (2) | 0 (0) |
| MF | 12 (3) | 8 (9) | 7 (15) | 9 (26) |
| MS | 55 (12) | 8 (9) | 9 (20) | 6 (17) |
| MY | 43 (10) | 7 (7) | 0 (0) | 0 (0) |
| PR | 30 (7) | 7 (7) | 19 (41) | 14 (40) |
Values in parentheses are percentages.