Comparison of sIL-6r ELISA and IL-6r GEP P values (t tests) in ND and MM by genotype and 1q21 status
| Comparison group . | ELISA P . | GEP P . |
|---|---|---|
| ND | ||
| AA-AC | < .001 | NA |
| AA-CC | < .001 | NA |
| AC-CC | .030 | NA |
| ND vs MM | ||
| All ND–All MM | < .001 | NA |
| AA ND–AA MM | .016 | NA |
| AC ND–AC MM | .015 | NA |
| CC ND–CC MM | .187 | NA |
| ND vs MM: 1q21 status and genotype | ||
| AA ND–AA MM NL | .122 | NA |
| AA ND–AA MM Amp | .001 | NA |
| AC ND–AC MM NL | .040 | NA |
| AC ND–AC MM Amp | .001 | NA |
| CC ND–CC MM NL | .287 | NA |
| CC ND–CC MM Amp | .051 | NA |
| MM | ||
| AA-AC | < .001 | .180 |
| AA-CC | < .001 | .315 |
| AC-CC | < .001 | .020 |
| NL-Amp | < .001 | < .001 |
| MM: like genotype, different 1q21 status | ||
| AA NL–AA Amp | < .001 | < .001 |
| AC NL–AC Amp | < .001 | < .001 |
| CC NL–CC Amp | < .001 | < .001 |
| MM: different genotype, different 1q21 status | ||
| AA NL–AC Amp | < .001 | < .001 |
| AA Amp–AC NL | .831 | < .001 |
| AA NL–CC Amp | < .001 | < .001 |
| AA Amp–CC NL | .002 | < .001 |
| AC NL–CC Amp | < .001 | < .001 |
| AC Amp–CC NL | .077 | < .001 |
| MM: different genotype, like 1q21 status | ||
| AA NL–AC NL | < .001 | .501 |
| AA Amp–AC Amp | < .001 | .579 |
| AA NL–CC NL | < .001 | .745 |
| AA Amp–CC Amp | < .001 | .135 |
| AC NL–CC NL | < .001 | .839 |
| AC Amp–CC Amp | < .001 | .025 |
| Comparison group . | ELISA P . | GEP P . |
|---|---|---|
| ND | ||
| AA-AC | < .001 | NA |
| AA-CC | < .001 | NA |
| AC-CC | .030 | NA |
| ND vs MM | ||
| All ND–All MM | < .001 | NA |
| AA ND–AA MM | .016 | NA |
| AC ND–AC MM | .015 | NA |
| CC ND–CC MM | .187 | NA |
| ND vs MM: 1q21 status and genotype | ||
| AA ND–AA MM NL | .122 | NA |
| AA ND–AA MM Amp | .001 | NA |
| AC ND–AC MM NL | .040 | NA |
| AC ND–AC MM Amp | .001 | NA |
| CC ND–CC MM NL | .287 | NA |
| CC ND–CC MM Amp | .051 | NA |
| MM | ||
| AA-AC | < .001 | .180 |
| AA-CC | < .001 | .315 |
| AC-CC | < .001 | .020 |
| NL-Amp | < .001 | < .001 |
| MM: like genotype, different 1q21 status | ||
| AA NL–AA Amp | < .001 | < .001 |
| AC NL–AC Amp | < .001 | < .001 |
| CC NL–CC Amp | < .001 | < .001 |
| MM: different genotype, different 1q21 status | ||
| AA NL–AC Amp | < .001 | < .001 |
| AA Amp–AC NL | .831 | < .001 |
| AA NL–CC Amp | < .001 | < .001 |
| AA Amp–CC NL | .002 | < .001 |
| AC NL–CC Amp | < .001 | < .001 |
| AC Amp–CC NL | .077 | < .001 |
| MM: different genotype, like 1q21 status | ||
| AA NL–AC NL | < .001 | .501 |
| AA Amp–AC Amp | < .001 | .579 |
| AA NL–CC NL | < .001 | .745 |
| AA Amp–CC Amp | < .001 | .135 |
| AC NL–CC NL | < .001 | .839 |
| AC Amp–CC Amp | < .001 | .025 |
AA, AC, and CC indicate rs2228145 genotype; and NA, not applicable.