Univariate and multivariate analysis of parameters impacting relapse
| Variable . | Univariate analysis . | Multivariate analysis* . | ||||
|---|---|---|---|---|---|---|
| RR . | 95% Cl . | P . | RR . | 95% CI . | P . | |
| Age | 0.98 | 0.96-1.00 | NS | NA | NA | .388 |
| Hemoglobin | 0.97 | 0.85-1.10 | NS | NA | NA | .786 |
| WBC, × 109/Lt | ||||||
| > 5 | 1.24 | 0.61-2.52 | NS | NA | NA | .776 |
| < 5 | ||||||
| Platelet, × 109/Lt | ||||||
| < 20 | 0.99 | 0.49-2.03 | NS | NA | NA | .243 |
| > 20 | ||||||
| RT-PCR positive at end of induction | 4.76 | 1.66-13.67 | 0.004 | 4.89 | 1.13-21.19 | .034 |
| RT-PCR positive before consolidation | 2.29 | 0.99-5.32 | NS | NA | NA | .257 |
| Additional cytogenetics | 3.58 | 1.61-7.98 | .002 | NA | NA | .063 |
| Variable . | Univariate analysis . | Multivariate analysis* . | ||||
|---|---|---|---|---|---|---|
| RR . | 95% Cl . | P . | RR . | 95% CI . | P . | |
| Age | 0.98 | 0.96-1.00 | NS | NA | NA | .388 |
| Hemoglobin | 0.97 | 0.85-1.10 | NS | NA | NA | .786 |
| WBC, × 109/Lt | ||||||
| > 5 | 1.24 | 0.61-2.52 | NS | NA | NA | .776 |
| < 5 | ||||||
| Platelet, × 109/Lt | ||||||
| < 20 | 0.99 | 0.49-2.03 | NS | NA | NA | .243 |
| > 20 | ||||||
| RT-PCR positive at end of induction | 4.76 | 1.66-13.67 | 0.004 | 4.89 | 1.13-21.19 | .034 |
| RT-PCR positive before consolidation | 2.29 | 0.99-5.32 | NS | NA | NA | .257 |
| Additional cytogenetics | 3.58 | 1.61-7.98 | .002 | NA | NA | .063 |
RR indicates relative risk; NS, not significant; and NA, not applicable.
Forward step-wise multivariate analysis.