Table 3

Mouse engraftment

Dose, cellsCD34+ total
CD34+CD38ALDHint
CD34+CD38ALDHhigh
ChimerismFISH+ChimerismFISH+ChimerismFISH+
100 000 0.92 ± 0.46 95.5 1.21 ± 0.49 98.5 ND NA 
10 000 0.12 ± 0.06 98 0.19 ± 0.06 98.5 1.33 ± 0.78 
1000 NA 0.14 ± 0.12 98 0.18 ± 0.16 0.5 
Dose, cellsCD34+ total
CD34+CD38ALDHint
CD34+CD38ALDHhigh
ChimerismFISH+ChimerismFISH+ChimerismFISH+
100 000 0.92 ± 0.46 95.5 1.21 ± 0.49 98.5 ND NA 
10 000 0.12 ± 0.06 98 0.19 ± 0.06 98.5 1.33 ± 0.78 
1000 NA 0.14 ± 0.12 98 0.18 ± 0.16 0.5 

Data are percentages (mean ± SEM) human CD45+ chimerism and the average percentage of those cells positive for leukemia by FISH.

ND indicates not done; and NA, not applicable.

Close Modal

or Create an Account

Close Modal
Close Modal