Microarray results of endothelial P2 receptor expression after TNF-α stimulation
| Gene . | TNF-α for 4 h (absolute fold change) . | TNF-α for 24 h (absolute fold change) . | Agilent array designation . |
|---|---|---|---|
| P2RY1 | 1.00 | 1.00 | A_23_P382835 |
| P2RY2 | 1.22 | 1.24 | A_23_P24903 |
| P2RY4 | 1.24 | 1.08 | A_23_P114307 |
| P2RY6 | 1.50 | 2.06* | A_23_P64611 |
| P2RY11 | 1.21 | 1.11 | A_23_P4696 |
| P2RY12 | 1.07 | 1.51 | A_23_P143902 |
| P2RY13 | 1.00 | 1.00 | A_23_P211948 |
| P2RY14 | 1.00 | 1.00 | A_24_P165864 |
| P2RX1 | 1.09 | 1.04 | A_23_P372848 |
| P2RX2 | 1.04 | 1.14 | A_23_P124003 |
| P2RX3 | 1.01 | 1.08 | A_23_P127721 |
| P2RX4 | 1.21 | 1.17 | A_23_P53623 |
| P2RX5 | 1.24 | 1.19 | A_23_P413760 |
| P2RX6 | 1.00 | 1.00 | A_23_P355980 |
| P2RX7 | 1.38 | 1.00 | A_24_P319113 |
| Gene . | TNF-α for 4 h (absolute fold change) . | TNF-α for 24 h (absolute fold change) . | Agilent array designation . |
|---|---|---|---|
| P2RY1 | 1.00 | 1.00 | A_23_P382835 |
| P2RY2 | 1.22 | 1.24 | A_23_P24903 |
| P2RY4 | 1.24 | 1.08 | A_23_P114307 |
| P2RY6 | 1.50 | 2.06* | A_23_P64611 |
| P2RY11 | 1.21 | 1.11 | A_23_P4696 |
| P2RY12 | 1.07 | 1.51 | A_23_P143902 |
| P2RY13 | 1.00 | 1.00 | A_23_P211948 |
| P2RY14 | 1.00 | 1.00 | A_24_P165864 |
| P2RX1 | 1.09 | 1.04 | A_23_P372848 |
| P2RX2 | 1.04 | 1.14 | A_23_P124003 |
| P2RX3 | 1.01 | 1.08 | A_23_P127721 |
| P2RX4 | 1.21 | 1.17 | A_23_P53623 |
| P2RX5 | 1.24 | 1.19 | A_23_P413760 |
| P2RX6 | 1.00 | 1.00 | A_23_P355980 |
| P2RX7 | 1.38 | 1.00 | A_24_P319113 |
Human microvascular endothelial cells (HMEC-1) were exposed to 100 ng/mL TNF-α for 24 hours. For each microarray, 3 different samples were pooled. RNA was isolated, and an Agilent Whole Genome Microarray was performed.
P of log ratio < .05.