Summary of NOD/SCID engraftment studies
| Sample . | Chimerism (%) . | Phenotype . | ||
|---|---|---|---|---|
| Bone marrow . | Spleen . | Liver . | ||
| MiNR1/MiGR1 m1 | 0.7 | n.d. | n.d. | No leukemia |
| MiNR1/MiGR1 m2 | 1.1 | n.d. | n.d. | No leukemia |
| MiNR1/MiGR1 m3 | 2.1 | n.d. | n.d. | No leukemia |
| BCR-ABL m1 | 1.5 | n.d. | n.d. | No leukemia, lymphoid/erythroid engraftment |
| BCR-ABL m2 | 2.2 | n.d. | n.d. | No leukemia, erythroid engraftment |
| BCR-ABL m3 | 10.6 | n.d. | n.d. | No leukemia, myeloid/erythroid engraftment |
| BCR-ABL m4 | 1.8 | n.d. | n.d. | No leukemia, lymphoid/erythroid engraftment |
| BMI1/BCR-ABL m1 | 76.4 | 49.9 | 74.5 | Leukemia, lymphoid, and erythroid engraftment |
| BMI1/BCR-ABL m2 | 61.8 | 50.8 | 77.3 | Leukemia, lymphoid, and erythroid engraftment |
| BMI1/BCR-ABL m3 | 1.2 | n.d. | n.d. | No leukemia |
| BMI1/BCR-ABL m4 | 0.5 | n.d. | n.d. | No leukemia |
| BMI1/BCR-ABL m5* | 53.8 | 59.2 | 63.8 | Leukemia, lymphoid, and erythroid engraftment |
| BMI1/BCR-ABL m6 | 5.6 | n.d. | n.d. | No leukemia |
| BMI1/BCR-ABL m7* | 89.4 | 59.1 | 59.3 | Leukemia, lymphoid, and erythroid engraftment |
| BMI1/BCR-ABL m8 | 4.3 | n.d. | n.d. | No leukemia |
| Sample . | Chimerism (%) . | Phenotype . | ||
|---|---|---|---|---|
| Bone marrow . | Spleen . | Liver . | ||
| MiNR1/MiGR1 m1 | 0.7 | n.d. | n.d. | No leukemia |
| MiNR1/MiGR1 m2 | 1.1 | n.d. | n.d. | No leukemia |
| MiNR1/MiGR1 m3 | 2.1 | n.d. | n.d. | No leukemia |
| BCR-ABL m1 | 1.5 | n.d. | n.d. | No leukemia, lymphoid/erythroid engraftment |
| BCR-ABL m2 | 2.2 | n.d. | n.d. | No leukemia, erythroid engraftment |
| BCR-ABL m3 | 10.6 | n.d. | n.d. | No leukemia, myeloid/erythroid engraftment |
| BCR-ABL m4 | 1.8 | n.d. | n.d. | No leukemia, lymphoid/erythroid engraftment |
| BMI1/BCR-ABL m1 | 76.4 | 49.9 | 74.5 | Leukemia, lymphoid, and erythroid engraftment |
| BMI1/BCR-ABL m2 | 61.8 | 50.8 | 77.3 | Leukemia, lymphoid, and erythroid engraftment |
| BMI1/BCR-ABL m3 | 1.2 | n.d. | n.d. | No leukemia |
| BMI1/BCR-ABL m4 | 0.5 | n.d. | n.d. | No leukemia |
| BMI1/BCR-ABL m5* | 53.8 | 59.2 | 63.8 | Leukemia, lymphoid, and erythroid engraftment |
| BMI1/BCR-ABL m6 | 5.6 | n.d. | n.d. | No leukemia |
| BMI1/BCR-ABL m7* | 89.4 | 59.1 | 59.3 | Leukemia, lymphoid, and erythroid engraftment |
| BMI1/BCR-ABL m8 | 4.3 | n.d. | n.d. | No leukemia |
n.d. indicates not determined.
Used for secondary transplantation.