Clinical features at HIV MCD diagnosis recorded in the systematic review of all published cases up to 2007 and in patients treated at Chelsea & Westminster Hospital, London
| . | Systematic review . | CWH series . |
|---|---|---|
| No. of patients | 72 | 56 |
| Median age, y (range) | 40 (21-67) | 42 (23-69) |
| Symptoms, no (%) | ||
| Fever | 72/72 (100) | 55/56 (98) |
| Lymphadenopathy | 69/72 (96) | 56/56 (100) |
| Splenomegaly | 62/72 (86) | 51/55* (93) |
| Hepatomegaly | 45/72 (63) | 36/56 (64) |
| Pulmonary signs or symptoms | 25/72 (35) | 27/56 (48) |
| Edema | 21/72 (29) | 6/56 (11) |
| Ascites | 4/72 (6) | 2/56 (4) |
| Kaposi sarcoma | 52/72 (72) | 30/56 (54) |
| Median CD4 cells/mm3 (range) | 160 (1-1050) | 234 (41-1429) |
| . | Systematic review . | CWH series . |
|---|---|---|
| No. of patients | 72 | 56 |
| Median age, y (range) | 40 (21-67) | 42 (23-69) |
| Symptoms, no (%) | ||
| Fever | 72/72 (100) | 55/56 (98) |
| Lymphadenopathy | 69/72 (96) | 56/56 (100) |
| Splenomegaly | 62/72 (86) | 51/55* (93) |
| Hepatomegaly | 45/72 (63) | 36/56 (64) |
| Pulmonary signs or symptoms | 25/72 (35) | 27/56 (48) |
| Edema | 21/72 (29) | 6/56 (11) |
| Ascites | 4/72 (6) | 2/56 (4) |
| Kaposi sarcoma | 52/72 (72) | 30/56 (54) |
| Median CD4 cells/mm3 (range) | 160 (1-1050) | 234 (41-1429) |
Data are from Mylona et al.7
One patient had had a splenectomy for idiopathic thrombocytopenic purpura before HIV MCD diagnosis.