Chromosomal abnormalities in AEtr-induced leukemias
| Mouse . | Tissue . | Karyotype . |
|---|---|---|
| 6114* | Spleen | 42, XX, +5, der(7)t(7;12)(F4;B), +15 [2] |
| 39, XX, der(7)t(7;10)(F3;C3)/−10 [2] | ||
| 42, XX, +4, +15 [1] | ||
| 39,XX, der(10;16)(A1;A1) [1] | ||
| 39, XX, −10,+11,−19 [1] | ||
| 78, XXXX, −2,−2,der(7)t(2;7)(F3;F3)×2, i(16)(A1)×2 [1] | ||
| 38, XX, +5,der(7)t(7;10)(F3;C3),−10,+11,−15,−18,−19 [1] | ||
| 40, XY [1] | ||
| 6115* | Spleen | 41, XX, +2, −10, +15 [1] |
| 41, X, −X or −Y, der(7)t(7;15)(F3;C), idic(10)(A3), +13, +13 [1] | ||
| 40, XX, der(7)t(7;12)(F4;B)del(12)(BD3), der(8)t(8;12)(A1;F1) [1] | ||
| 40, X, −X, +2, −3, der(7)t(7;12)(F4;B)del(12)(BD3), del(9)(A4F3)+15 [1] | ||
| 40, XX, −2, der(7)t(7;12)(F4;B)del(12)(BD3), +15 [1] | ||
| 39, XY, +5, t(5;12)(B1;A1), −12, −16 [1] | ||
| 36, XX, −2,der(7)t(2;7)(H1;F3), −13, −16, −17 [1] | ||
| 40, XX [2] | ||
| 6266 | Spleen | 41, XY, +12 [4] |
| 40, XY [6] | ||
| 6107 | Spleen | 40, XY [10] |
| 3419 | Spleen | 80, XXXX [4] |
| 40, XX [6] | ||
| 2625 | Spleen | 41, XX, +15 [4] |
| 40, XX [6] | ||
| 1680* | Blood | 40, XY [8] |
| 40, XX [2] | ||
| 1347 | Spleen | 40, XY, t(1;15)(H1;C) [2] |
| 40, idem,t(6;11)(A1;B3) [2] | ||
| 40, XY, t(1;11)(H5;B3), t(2;4)(D;B1) [2] | ||
| 40, XY, t(2;7)(H3;F1) [1] | ||
| 40, XY, t(1;7;17;13)(F;F1;D;B) [1] | ||
| 39, XY, −7, t(9;11)(D;B3) [1] | ||
| 40, XY [1] |
| Mouse . | Tissue . | Karyotype . |
|---|---|---|
| 6114* | Spleen | 42, XX, +5, der(7)t(7;12)(F4;B), +15 [2] |
| 39, XX, der(7)t(7;10)(F3;C3)/−10 [2] | ||
| 42, XX, +4, +15 [1] | ||
| 39,XX, der(10;16)(A1;A1) [1] | ||
| 39, XX, −10,+11,−19 [1] | ||
| 78, XXXX, −2,−2,der(7)t(2;7)(F3;F3)×2, i(16)(A1)×2 [1] | ||
| 38, XX, +5,der(7)t(7;10)(F3;C3),−10,+11,−15,−18,−19 [1] | ||
| 40, XY [1] | ||
| 6115* | Spleen | 41, XX, +2, −10, +15 [1] |
| 41, X, −X or −Y, der(7)t(7;15)(F3;C), idic(10)(A3), +13, +13 [1] | ||
| 40, XX, der(7)t(7;12)(F4;B)del(12)(BD3), der(8)t(8;12)(A1;F1) [1] | ||
| 40, X, −X, +2, −3, der(7)t(7;12)(F4;B)del(12)(BD3), del(9)(A4F3)+15 [1] | ||
| 40, XX, −2, der(7)t(7;12)(F4;B)del(12)(BD3), +15 [1] | ||
| 39, XY, +5, t(5;12)(B1;A1), −12, −16 [1] | ||
| 36, XX, −2,der(7)t(2;7)(H1;F3), −13, −16, −17 [1] | ||
| 40, XX [2] | ||
| 6266 | Spleen | 41, XY, +12 [4] |
| 40, XY [6] | ||
| 6107 | Spleen | 40, XY [10] |
| 3419 | Spleen | 80, XXXX [4] |
| 40, XX [6] | ||
| 2625 | Spleen | 41, XX, +15 [4] |
| 40, XX [6] | ||
| 1680* | Blood | 40, XY [8] |
| 40, XX [2] | ||
| 1347 | Spleen | 40, XY, t(1;15)(H1;C) [2] |
| 40, idem,t(6;11)(A1;B3) [2] | ||
| 40, XY, t(1;11)(H5;B3), t(2;4)(D;B1) [2] | ||
| 40, XY, t(2;7)(H3;F1) [1] | ||
| 40, XY, t(1;7;17;13)(F;F1;D;B) [1] | ||
| 39, XY, −7, t(9;11)(D;B3) [1] | ||
| 40, XY [1] |
Spectral karyotype analysis of 8 primary murine leukemias induced by transplantation of hematopoietic cells expressing AEtr. A minimum of 10 metaphase cells per leukemia sample was analyzed. Mouse identification, tissue of origin, and karyotype are indicated for each sample.
Metaphase cells derived from both donor and recipient mice were observed.