Results of multivariate analysis in which donor availability, prognostic category, and age were considered
| Parameter . | Overall survival . | Disease-free survival . | Relapse . | ||||||
|---|---|---|---|---|---|---|---|---|---|
| HR . | 95% CI . | P . | HR . | 95% CI . | P . | HR . | 95% CI . | P . | |
| Donor availability* | 0.85 | (0.70–1.03) | .09 | 0.71 | (0.59–0.85) | < .001 | 0.46 | (0.37–0.57) | < .001 |
| Prognostic category† | < .001 | < .001 | < .001 | ||||||
| Intermediate | 2.50 | (1.67–3.76) | 1.83 | (1.30–2.56) | 1.97 | (1.35–2.87) | |||
| Poor risk | 4.53 | (3.01–6.83) | 3.49 | (2.48–4.90) | 3.67 | (2.51–5.38) | |||
| Age older than 40‡ | 1.39 | (1.16–1.67) | < .001 | 1.23 | (1.03–1.45) | .02 | 1.19 | (0.98–1.43) | .07 |
| Parameter . | Overall survival . | Disease-free survival . | Relapse . | ||||||
|---|---|---|---|---|---|---|---|---|---|
| HR . | 95% CI . | P . | HR . | 95% CI . | P . | HR . | 95% CI . | P . | |
| Donor availability* | 0.85 | (0.70–1.03) | .09 | 0.71 | (0.59–0.85) | < .001 | 0.46 | (0.37–0.57) | < .001 |
| Prognostic category† | < .001 | < .001 | < .001 | ||||||
| Intermediate | 2.50 | (1.67–3.76) | 1.83 | (1.30–2.56) | 1.97 | (1.35–2.87) | |||
| Poor risk | 4.53 | (3.01–6.83) | 3.49 | (2.48–4.90) | 3.67 | (2.51–5.38) | |||
| Age older than 40‡ | 1.39 | (1.16–1.67) | < .001 | 1.23 | (1.03–1.45) | .02 | 1.19 | (0.98–1.43) | .07 |
Prognostic category according to cytogenetics, WBC count, and early or late attainment of CR (see “Patients, materials, and Methods”).
HR indicates hazard ratio; CI, confidence interval.
*In comparison with no donor group.
†In comparison with good-risk group.
‡In comparison with age younger than 40 group.