Table 1

Risk group classification

GroupDefinition
Good t(8;21) and WBC count ≤ 20 × 109/L and no additional unfavorable cytogenetic abnormalities; inv/del(16) and no additional unfavorable cytogenetic abnormalities 
Intermediate Patients not assigned to good or poor-risk groups 
Poor Unfavorable cytogenetics: complex karyotypes (≥3); del(5q)/−5; del(7q)/−7; abn(3q); t(6;9)/t(9;22); abn(11q23); and late CR* 
GroupDefinition
Good t(8;21) and WBC count ≤ 20 × 109/L and no additional unfavorable cytogenetic abnormalities; inv/del(16) and no additional unfavorable cytogenetic abnormalities 
Intermediate Patients not assigned to good or poor-risk groups 
Poor Unfavorable cytogenetics: complex karyotypes (≥3); del(5q)/−5; del(7q)/−7; abn(3q); t(6;9)/t(9;22); abn(11q23); and late CR* 

CR indicates complete remission; WBC, white blood cell.

*Except patients with favorable cytogenetics

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