Proportion of CD4 and CD8 T lymphocytes expressing CCR6 chemokine receptors in UI and HIV-infected individuals
. | UI . | HIV+ . | ||||
---|---|---|---|---|---|---|
% . | Cells/mm3 . | Range . | % . | Cells/mm3 . | Range . | |
CD4+ | 44 ± 2 | 820 ± 88 | 601-1331 | 21 ± 2* | 388 ± 53† | 10-784 |
CD8+ | 26 ± 3 | 540 ± 107 | 167-1056 | 51 ± 3* | 920 ± 96‡ | 156-1751 |
CCR6+ among CD4+ | 31 ± 2 | 258 ± 22 | 137-395 | 26 ± 2 | 106 ± 16* | 3-194 |
CCR6+ among CD8+ | 13 ± 1 | 67 ± 7 | 19-165 | 4 ± 1* | 37 ± 5† | 2-80 |
. | UI . | HIV+ . | ||||
---|---|---|---|---|---|---|
% . | Cells/mm3 . | Range . | % . | Cells/mm3 . | Range . | |
CD4+ | 44 ± 2 | 820 ± 88 | 601-1331 | 21 ± 2* | 388 ± 53† | 10-784 |
CD8+ | 26 ± 3 | 540 ± 107 | 167-1056 | 51 ± 3* | 920 ± 96‡ | 156-1751 |
CCR6+ among CD4+ | 31 ± 2 | 258 ± 22 | 137-395 | 26 ± 2 | 106 ± 16* | 3-194 |
CCR6+ among CD8+ | 13 ± 1 | 67 ± 7 | 19-165 | 4 ± 1* | 37 ± 5† | 2-80 |
Proportions of CD4+ or CD8+ T cells and proportions of CD4+ and CD8+ T cells expressing chemokine receptor CCR6, reported as percentage ± standard error of the mean (SEM) and as number of cells/mm3 of peripheral blood ± SEM, with their ranges. Twenty-two HIV-infected patients and 27 UI individuals were sampled. The mean viral load of HIV-infected patients was 24 929 copies/mL, with a range of < 200 to 420 000 number of copies/mL.
*P < .001.
†P < .01.
‡P < .05.