Discounted life expectancy
| Decision at CR1 . | All patients . | Younger patients (median age, 35 y) . | Older patients (median age, 60 y) . | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LE . | QALE . | LE . | QALE . | LE . | QALE . | |||||||
| Allo-HCT . | CTx . | Allo-HCT . | CTx . | Allo-HCT . | CTx . | Allo-HCT . | CTx . | Allo-HCT . | CTx . | Allo-HCT . | CTx . | |
| Total | 69.7 | 66.7 | 55.9 | 55.4 | 71.4 | 73.2 | 57.7 | 60.2 | 65.8 | 60.0 | 52.1 | 50.6 |
| Cytogenetic risks (SWOG) | ||||||||||||
| Favorable | 69.6 | 77.0 | 56.0 | 64.3 | 67.0 | 82.3 | 53.8 | 67.6 | ||||
| Intermediate | 73.6 | 66.4 | 59.4 | 55.6 | 76.2 | 75.1 | 62.0 | 62.4 | 68.5 | 60.7 | 54.5 | 51.4 |
| Unfavorable | 61.6 | 53.4 | 47.6 | 44.4 | 62.8 | 55.3 | 48.7 | 44.8 | 61.6 | 53.3 | 46.0 | 45.0 |
| Unknown | 65.6 | 59.3 | 54.1 | 46.8 | 67.4 | 68.3 | 56.3 | 53.6 | 63.1 | 48.8 | 50.6 | 38.9 |
| Other than favorable | 69.5 | 62.5 | 55.8 | 52.0 | ||||||||
| Donor availability | ||||||||||||
| Related donor | 72.2 | 63.0 | 57.6 | 49.9 | 73.0 | 67.6 | 58.3 | 54.2 | 73.4 | 53.2 | 57.7 | 40.4 |
| No related donor | 67.7 | 67.0 | 54.6 | 54.4 | 71.0 | 70.7 | 57.7 | 57.2 | 57.4 | 57.7 | 45.4 | 46.8 |
| Donor availability (other than favorable-risk) | ||||||||||||
| Related donor | 72.0 | 60.5 | 57.2 | 47.6 | ||||||||
| No related donor | 67.3 | 64.2 | 54.5 | 52.2 | ||||||||
| Decision at CR1 . | All patients . | Younger patients (median age, 35 y) . | Older patients (median age, 60 y) . | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LE . | QALE . | LE . | QALE . | LE . | QALE . | |||||||
| Allo-HCT . | CTx . | Allo-HCT . | CTx . | Allo-HCT . | CTx . | Allo-HCT . | CTx . | Allo-HCT . | CTx . | Allo-HCT . | CTx . | |
| Total | 69.7 | 66.7 | 55.9 | 55.4 | 71.4 | 73.2 | 57.7 | 60.2 | 65.8 | 60.0 | 52.1 | 50.6 |
| Cytogenetic risks (SWOG) | ||||||||||||
| Favorable | 69.6 | 77.0 | 56.0 | 64.3 | 67.0 | 82.3 | 53.8 | 67.6 | ||||
| Intermediate | 73.6 | 66.4 | 59.4 | 55.6 | 76.2 | 75.1 | 62.0 | 62.4 | 68.5 | 60.7 | 54.5 | 51.4 |
| Unfavorable | 61.6 | 53.4 | 47.6 | 44.4 | 62.8 | 55.3 | 48.7 | 44.8 | 61.6 | 53.3 | 46.0 | 45.0 |
| Unknown | 65.6 | 59.3 | 54.1 | 46.8 | 67.4 | 68.3 | 56.3 | 53.6 | 63.1 | 48.8 | 50.6 | 38.9 |
| Other than favorable | 69.5 | 62.5 | 55.8 | 52.0 | ||||||||
| Donor availability | ||||||||||||
| Related donor | 72.2 | 63.0 | 57.6 | 49.9 | 73.0 | 67.6 | 58.3 | 54.2 | 73.4 | 53.2 | 57.7 | 40.4 |
| No related donor | 67.7 | 67.0 | 54.6 | 54.4 | 71.0 | 70.7 | 57.7 | 57.2 | 57.4 | 57.7 | 45.4 | 46.8 |
| Donor availability (other than favorable-risk) | ||||||||||||
| Related donor | 72.0 | 60.5 | 57.2 | 47.6 | ||||||||
| No related donor | 67.3 | 64.2 | 54.5 | 52.2 | ||||||||
Life expectancies are shown in months.
LE indicates life expectancy; QALE, quality of life–adjusted life expectancy; allo-HCT, allogeneic hematopoietic cell transplantation; and CTx, chemotherapy.