Safety outcomes: most common adverse events with obinutuzumab
| Most common AEs . | No. of patients with at least 1 AE, n (%) . | |
|---|---|---|
| All grades . | Grade 3/4 . | |
| During induction, n = 22 | ||
| Infusion-related reaction | 16 (73) | 4 (18) |
| Infection | 7 (32) | |
| Pyrexia | 5 (23) | |
| Neutropenia | 5 (23) | 5 (23) |
| Headache | 4 (18) | 1 (4) |
| Nausea | 4 (18) | |
| Diarrhea | 3 (14) | |
| Fatigue | 3 (14) | |
| During maintenance, n = 8 | ||
| Infection | 5 (62) | 1 (13) |
| Infusion-related reaction | 2 (25) | |
| Cough | 2 (25) | |
| Most common AEs . | No. of patients with at least 1 AE, n (%) . | |
|---|---|---|
| All grades . | Grade 3/4 . | |
| During induction, n = 22 | ||
| Infusion-related reaction | 16 (73) | 4 (18) |
| Infection | 7 (32) | |
| Pyrexia | 5 (23) | |
| Neutropenia | 5 (23) | 5 (23) |
| Headache | 4 (18) | 1 (4) |
| Nausea | 4 (18) | |
| Diarrhea | 3 (14) | |
| Fatigue | 3 (14) | |
| During maintenance, n = 8 | ||
| Infection | 5 (62) | 1 (13) |
| Infusion-related reaction | 2 (25) | |
| Cough | 2 (25) | |
Data are as of the August 2010 cutoff.