Pairwise frequency of biomarkers
| . | Score . | BCL6 score . | CD10 score . | CD5 score . | HLA-DR score . | Ki67 score . | MUM1 score . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No staining . | Staining . | No staining . | Staining . | ≤75% . | >75% . | No staining . | Staining . | ≤75% . | >75% . | ≤75% . | >75% . | ||
| BCL2 | 0%-75% | 56 (12%) | 433 (88%) | 378 (59%) | 267 (41%) | 615 (95%)* | 33 (5%)* | 75 (12%) | 569 (88%) | 233 (42%) | 328 (58%) | 514 (85%)* | 89 (15%)* |
| > 75% | 58 (13%) | 381 (87%) | 351 (57%) | 265 (43%) | 554 (87%)* | 81 (13%)* | 86 (13%) | 553 (87%) | 246 (48%) | 267 (52%) | 410 (71%)* | 169 (29%)* | |
| BCL6 | No staining | 96 (82%)* | 21 (18%)* | 104 (87%) | 15 (13%) | 14 (11%) | 109 (89%) | 49 (44%) | 62 (56%) | 78 (68%) | 37 (32%) | ||
| Staining | 411 (49%)* | 422 (51%)* | 789 (93%) | 56 (7%) | 93 (11%) | 750 (89%) | 331 (42%) | 458 (58%) | 642 (79%) | 174 (21%) | |||
| CD10 | No staining | 669 (89%)* | 84 (11%)* | 109 (14%) | 643 (86%) | 298 (47%) | 332 (53%) | 503 (72%)* | 200 (28%)* | ||||
| Staining | 529 (95%)* | 29 (5%)* | 60 (11%) | 502 (89%) | 183 (39%) | 286 (61%) | 440 (89%)* | 56 (11%)* | |||||
| CD5 | 0%-75% | 154 (13%) | 1057 (87%) | 448 (44%) | 572 (56%) | 880 (79%) | 235 (21%) | ||||||
| > 75% | 15 (12%) | 105 (88%) | 40 (43%) | 54 (57%) | 77 (71%) | 31 (29%) | |||||||
| HLA-DR | No staining | 51 (37%) | 88 (63%) | 100 (66%)* | 52 (34%)* | ||||||||
| Staining | 442 (45%) | 534 (55%) | 858 (80%)* | 209 (20%)* | |||||||||
| Ki67 | 0%-75% | 408 (87%)* | 60 (13%)* | ||||||||||
| > 75% | 424 (69%)* | 187 (31%)* | |||||||||||
| . | Score . | BCL6 score . | CD10 score . | CD5 score . | HLA-DR score . | Ki67 score . | MUM1 score . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No staining . | Staining . | No staining . | Staining . | ≤75% . | >75% . | No staining . | Staining . | ≤75% . | >75% . | ≤75% . | >75% . | ||
| BCL2 | 0%-75% | 56 (12%) | 433 (88%) | 378 (59%) | 267 (41%) | 615 (95%)* | 33 (5%)* | 75 (12%) | 569 (88%) | 233 (42%) | 328 (58%) | 514 (85%)* | 89 (15%)* |
| > 75% | 58 (13%) | 381 (87%) | 351 (57%) | 265 (43%) | 554 (87%)* | 81 (13%)* | 86 (13%) | 553 (87%) | 246 (48%) | 267 (52%) | 410 (71%)* | 169 (29%)* | |
| BCL6 | No staining | 96 (82%)* | 21 (18%)* | 104 (87%) | 15 (13%) | 14 (11%) | 109 (89%) | 49 (44%) | 62 (56%) | 78 (68%) | 37 (32%) | ||
| Staining | 411 (49%)* | 422 (51%)* | 789 (93%) | 56 (7%) | 93 (11%) | 750 (89%) | 331 (42%) | 458 (58%) | 642 (79%) | 174 (21%) | |||
| CD10 | No staining | 669 (89%)* | 84 (11%)* | 109 (14%) | 643 (86%) | 298 (47%) | 332 (53%) | 503 (72%)* | 200 (28%)* | ||||
| Staining | 529 (95%)* | 29 (5%)* | 60 (11%) | 502 (89%) | 183 (39%) | 286 (61%) | 440 (89%)* | 56 (11%)* | |||||
| CD5 | 0%-75% | 154 (13%) | 1057 (87%) | 448 (44%) | 572 (56%) | 880 (79%) | 235 (21%) | ||||||
| > 75% | 15 (12%) | 105 (88%) | 40 (43%) | 54 (57%) | 77 (71%) | 31 (29%) | |||||||
| HLA-DR | No staining | 51 (37%) | 88 (63%) | 100 (66%)* | 52 (34%)* | ||||||||
| Staining | 442 (45%) | 534 (55%) | 858 (80%)* | 209 (20%)* | |||||||||
| Ki67 | 0%-75% | 408 (87%)* | 60 (13%)* | ||||||||||
| > 75% | 424 (69%)* | 187 (31%)* | |||||||||||
Biomarkers that are significantly (P < .002) correlated. Adjusting for multiple comparisons using the Bonferroni method, χ2P values < .05/21 are considered significant.