Table 1 Hematologic parameters, spleen... | American Society of Hematology

Table 1

Hematologic parameters, spleen weight, and serum Epo levels at different time points for each experimental condition

Condition	RBCs, ×10⁶/μL	Reticulocytes, ×10³/μL	Hb, g/dL	MCV, fL	Spleen weight, mg	Serum Epo, pg/mL
Controls	9.45 ± 0.67	28 ± 4.7	14.1 ± 1.07	48.51 ± 3.05	81 ± 9	94
Zymosan
Z5	7.30 ± 0.8*	11 ± 1.52*	10.8 ± 0.86*	44.47 ± 0.57	189 ± 37*	290
Z9	6.76 ± 0.7*	20 ± 5.46	9.8 ± 1.01*	47.22 ± 3.11	322 ± 18.9*
Z12	7.29 ± 0.76*	32 ± 8.7	10.1 ± 0.97*	48.28 ± 0.31	419 ± 150*	499
Z17	6.23 ± 0.2*	47 ± 0.5*	7.8 ± 0.22*	45.03 ± 0.79	481 ± 112*
Epo
Epo1	10.71 ± 0.61*	83 ± 12.79*	16.5 ± 1.16*	49.34 ± 1.46	266 ± 42.2*	1060
Epo4	11.24 ± 0.5*	29 ± 10.38*	17.4 ± 0.91*	50.80 ± 0.97	80 ± 15.15	100
Zymosan + Epo
Z9Epo1	7.43 ± 0.29*	40 ± 7.37*†	10.8 ± 0.45*	46.63 ± 0.80	355 ± 74*	284
Z12Epo4	8.20 ± 0.36*	33 ± 6.34	11.9 ± 0.85*	49.05 ± 2.08	445 ± 130*	192
Z17Epo9	7.68 ± 0.8*‡	51 ± 12.78*	11.2 ± 1.18*‡	44.55 ± 1.4	269 ± 39.1*‡	111

Condition	RBCs, ×10⁶/μL	Reticulocytes, ×10³/μL	Hb, g/dL	MCV, fL	Spleen weight, mg	Serum Epo, pg/mL
Controls	9.45 ± 0.67	28 ± 4.7	14.1 ± 1.07	48.51 ± 3.05	81 ± 9	94
Zymosan
Z5	7.30 ± 0.8*	11 ± 1.52*	10.8 ± 0.86*	44.47 ± 0.57	189 ± 37*	290
Z9	6.76 ± 0.7*	20 ± 5.46	9.8 ± 1.01*	47.22 ± 3.11	322 ± 18.9*
Z12	7.29 ± 0.76*	32 ± 8.7	10.1 ± 0.97*	48.28 ± 0.31	419 ± 150*	499
Z17	6.23 ± 0.2*	47 ± 0.5*	7.8 ± 0.22*	45.03 ± 0.79	481 ± 112*
Epo
Epo1	10.71 ± 0.61*	83 ± 12.79*	16.5 ± 1.16*	49.34 ± 1.46	266 ± 42.2*	1060
Epo4	11.24 ± 0.5*	29 ± 10.38*	17.4 ± 0.91*	50.80 ± 0.97	80 ± 15.15	100
Zymosan + Epo
Z9Epo1	7.43 ± 0.29*	40 ± 7.37*†	10.8 ± 0.45*	46.63 ± 0.80	355 ± 74*	284
Z12Epo4	8.20 ± 0.36*	33 ± 6.34	11.9 ± 0.85*	49.05 ± 2.08	445 ± 130*	192
Z17Epo9	7.68 ± 0.8*‡	51 ± 12.78*	11.2 ± 1.18*‡	44.55 ± 1.4	269 ± 39.1*‡	111

Data are mean ± SEM. Data correspond to the results obtained from a pool of 4 sera from 4 different mice.

MCV indicates mean corpuscular volume.

P < .02 compared with controls.

P < .03 compared with Z9.

P < .007 compared with Z17.