Infection rates by prognostic factors in univariate and multivariate analysis
Parameter/group . | Patients, n . | Patients with infection . | |||
---|---|---|---|---|---|
Univariate . | Multivariate . | ||||
n . | % . | P . | P . | ||
Baseline leukocytes, /μL | |||||
< 4000 | 88 | 67 | 76 | .0086 | .61 |
≥ 4000 | 80 | 45 | 56 | ||
Previous radiotherapy | |||||
No | 109 | 73 | 67 | 1.0 | – |
Yes | 59 | 39 | 66 | ||
Previous cycles of chemotherapy | |||||
≤ 6 | 120 | 72 | 60 | .0053 | .16 |
> 6 | 48 | 40 | 83 | ||
CD34+ cells, ×106/kg | |||||
2.0-5.0 | 106 | 73 | 69 | .50 | – |
> 5.0 | 62 | 39 | 63 | ||
High-dose chemotherapy | |||||
Melphalan | 104 | 60 | 58 | .0022 | .80 |
BEAM and others | 64 | 52 | 81 | ||
G-CSF responsiveness | |||||
Low | 43 | 39 | 91 | < .0001 | .016 |
Medium | 42 | 28 | 67 | ||
High | 83 | 45 | 54 |
Parameter/group . | Patients, n . | Patients with infection . | |||
---|---|---|---|---|---|
Univariate . | Multivariate . | ||||
n . | % . | P . | P . | ||
Baseline leukocytes, /μL | |||||
< 4000 | 88 | 67 | 76 | .0086 | .61 |
≥ 4000 | 80 | 45 | 56 | ||
Previous radiotherapy | |||||
No | 109 | 73 | 67 | 1.0 | – |
Yes | 59 | 39 | 66 | ||
Previous cycles of chemotherapy | |||||
≤ 6 | 120 | 72 | 60 | .0053 | .16 |
> 6 | 48 | 40 | 83 | ||
CD34+ cells, ×106/kg | |||||
2.0-5.0 | 106 | 73 | 69 | .50 | – |
> 5.0 | 62 | 39 | 63 | ||
High-dose chemotherapy | |||||
Melphalan | 104 | 60 | 58 | .0022 | .80 |
BEAM and others | 64 | 52 | 81 | ||
G-CSF responsiveness | |||||
Low | 43 | 39 | 91 | < .0001 | .016 |
Medium | 42 | 28 | 67 | ||
High | 83 | 45 | 54 |
G-CSF indicates granulocyte colony-stimulating factor.