Table 4

Infection rates by prognostic factors in univariate and multivariate analysis

Parameter/groupPatients, nPatients with infection
Univariate
Multivariate
n%PP
Baseline leukocytes, /μL      
    < 4000 88 67 76 .0086 .61 
    ≥ 4000 80 45 56   
Previous radiotherapy      
    No 109 73 67 1.0 – 
    Yes 59 39 66   
Previous cycles of chemotherapy      
    ≤ 6 120 72 60 .0053 .16 
    > 6 48 40 83   
CD34+ cells, ×106/kg      
    2.0-5.0 106 73 69 .50 – 
    > 5.0 62 39 63   
High-dose chemotherapy      
    Melphalan 104 60 58 .0022 .80 
    BEAM and others 64 52 81   
G-CSF responsiveness      
    Low 43 39 91 < .0001 .016 
    Medium 42 28 67   
    High 83 45 54   
Parameter/groupPatients, nPatients with infection
Univariate
Multivariate
n%PP
Baseline leukocytes, /μL      
    < 4000 88 67 76 .0086 .61 
    ≥ 4000 80 45 56   
Previous radiotherapy      
    No 109 73 67 1.0 – 
    Yes 59 39 66   
Previous cycles of chemotherapy      
    ≤ 6 120 72 60 .0053 .16 
    > 6 48 40 83   
CD34+ cells, ×106/kg      
    2.0-5.0 106 73 69 .50 – 
    > 5.0 62 39 63   
High-dose chemotherapy      
    Melphalan 104 60 58 .0022 .80 
    BEAM and others 64 52 81   
G-CSF responsiveness      
    Low 43 39 91 < .0001 .016 
    Medium 42 28 67   
    High 83 45 54   

G-CSF indicates granulocyte colony-stimulating factor.

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