Table 3 Univariate survival analysis of... | American Society of Hematology

Table 3

Univariate survival analysis of the complete cohort (n = 733)

	Complete cohort
	n	EFS	P (log-rank)	OS	P (log-rank)	CIR	P (Gray)
Additional aberrations			.002†		< .001†		< .001†
Absent	389	0.48		0.62		0.38
Present	344	0.38		0.47		0.52
No. of aberrations			< .001†		< .001†		.001†
2	152	0.39		0.50		0.50
3	80	0.45		0.53		0.48
≥ 3	192	0.37	.018*	0.45	.003†	0.53	< .001†
4	44	0.40		0.50		0.53
5	25	0.36		0.43		0.60
> 5	43	0.18	< .001†	0.25		0.61
Type			.001†		.003†		< .001†
Numerical	140	0.47		0.56		0.41
Structural	130	0.32		0.43		0.59
Both	74	0.31		0.40		0.59
Trisomy
4	20	0.43	.72	0.52	.87	0.52	.93
6	36	0.35	.43	0.35	.029*	0.54	.65
8	130	0.53	< .001†	0.61	.003†	0.35	< .001†
13	18	0.49	.52	0.64	.41	0.40	.37
19	37	0.17	.003†	0.24	< .001†	0.54	.88
21	35	0.19	.007†	0.28	.015*	0.69	.014*

	Complete cohort
	n	EFS	P (log-rank)	OS	P (log-rank)	CIR	P (Gray)
Additional aberrations			.002†		< .001†		< .001†
Absent	389	0.48		0.62		0.38
Present	344	0.38		0.47		0.52
No. of aberrations			< .001†		< .001†		.001†
2	152	0.39		0.50		0.50
3	80	0.45		0.53		0.48
≥ 3	192	0.37	.018*	0.45	.003†	0.53	< .001†
4	44	0.40		0.50		0.53
5	25	0.36		0.43		0.60
> 5	43	0.18	< .001†	0.25		0.61
Type			.001†		.003†		< .001†
Numerical	140	0.47		0.56		0.41
Structural	130	0.32		0.43		0.59
Both	74	0.31		0.40		0.59
Trisomy
4	20	0.43	.72	0.52	.87	0.52	.93
6	36	0.35	.43	0.35	.029*	0.54	.65
8	130	0.53	< .001†	0.61	.003†	0.35	< .001†
13	18	0.49	.52	0.64	.41	0.40	.37
19	37	0.17	.003†	0.24	< .001†	0.54	.88
21	35	0.19	.007†	0.28	.015*	0.69	.014*

CIR, indicates 5-year cumulative incidence of relapse; EFS, 5-year event-free survival estimates; n, number of patients; OS, 5-year overall survival estimate; P (Gray), P value from the Gray test; and P (log-rank), P value from log-rank test.

Significant at P < .05 level.

†

Significant at P < .01 level.

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