Table 3

Recurrent CNAs in FL

Column A (chromosome arm)Column B (chromosome band)Column C (n = 44), n (%)
Gains   
    1q 1q22 22 (50) 
    2p 2p16 11 (25) 
    6p 6p21p25 7 (16) 
    7p 7p22 12 (27) 
    7q 7q11 16 (36) 
    8q 8q24 7 (16) 
    11p 11p11 7 (16) 
    12q 12q13 9 (21) 
    16p 16p13 9 (21) 
    17p 17p11 7 (16) 
    17q 17q21 12 (27) 
    18 18p11q21 18 (41) 
    19p 19p13 11 (25) 
    19q 19q13 10 (23) 
    21 21q21 8 (18) 
    X Xp11q21 25 (57) 
Losses   
    1p 1p36 10 (23) 
    6q 6q23q25 12 (27) 
    13q 13q34 8 (18) 
Column A (chromosome arm)Column B (chromosome band)Column C (n = 44), n (%)
Gains   
    1q 1q22 22 (50) 
    2p 2p16 11 (25) 
    6p 6p21p25 7 (16) 
    7p 7p22 12 (27) 
    7q 7q11 16 (36) 
    8q 8q24 7 (16) 
    11p 11p11 7 (16) 
    12q 12q13 9 (21) 
    16p 16p13 9 (21) 
    17p 17p11 7 (16) 
    17q 17q21 12 (27) 
    18 18p11q21 18 (41) 
    19p 19p13 11 (25) 
    19q 19q13 10 (23) 
    21 21q21 8 (18) 
    X Xp11q21 25 (57) 
Losses   
    1p 1p36 10 (23) 
    6q 6q23q25 12 (27) 
    13q 13q34 8 (18) 

Column A indicates chromosome arms with copy number alterations in more than 15% of the first examined biopsies from all patients (n = 44). Chr 18 and X were the only ones with gain of the whole chromosome in more than 15% of the cases, and a whole chromosome gain was seen in 9 (21%) and 20 (46%) of the cases, respectively. Column B indicates chromosome bands with the highest frequency of gain or loss within the arm specified in column A. Column C indicates the number and frequency of cases harboring gain or loss in the region specified in column B.

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