Recurrent CNAs in FL
Column A (chromosome arm) . | Column B (chromosome band) . | Column C (n = 44), n (%) . |
---|---|---|
Gains | ||
1q | 1q22 | 22 (50) |
2p | 2p16 | 11 (25) |
6p | 6p21p25 | 7 (16) |
7p | 7p22 | 12 (27) |
7q | 7q11 | 16 (36) |
8q | 8q24 | 7 (16) |
11p | 11p11 | 7 (16) |
12q | 12q13 | 9 (21) |
16p | 16p13 | 9 (21) |
17p | 17p11 | 7 (16) |
17q | 17q21 | 12 (27) |
18 | 18p11q21 | 18 (41) |
19p | 19p13 | 11 (25) |
19q | 19q13 | 10 (23) |
21 | 21q21 | 8 (18) |
X | Xp11q21 | 25 (57) |
Losses | ||
1p | 1p36 | 10 (23) |
6q | 6q23q25 | 12 (27) |
13q | 13q34 | 8 (18) |
Column A (chromosome arm) . | Column B (chromosome band) . | Column C (n = 44), n (%) . |
---|---|---|
Gains | ||
1q | 1q22 | 22 (50) |
2p | 2p16 | 11 (25) |
6p | 6p21p25 | 7 (16) |
7p | 7p22 | 12 (27) |
7q | 7q11 | 16 (36) |
8q | 8q24 | 7 (16) |
11p | 11p11 | 7 (16) |
12q | 12q13 | 9 (21) |
16p | 16p13 | 9 (21) |
17p | 17p11 | 7 (16) |
17q | 17q21 | 12 (27) |
18 | 18p11q21 | 18 (41) |
19p | 19p13 | 11 (25) |
19q | 19q13 | 10 (23) |
21 | 21q21 | 8 (18) |
X | Xp11q21 | 25 (57) |
Losses | ||
1p | 1p36 | 10 (23) |
6q | 6q23q25 | 12 (27) |
13q | 13q34 | 8 (18) |
Column A indicates chromosome arms with copy number alterations in more than 15% of the first examined biopsies from all patients (n = 44). Chr 18 and X were the only ones with gain of the whole chromosome in more than 15% of the cases, and a whole chromosome gain was seen in 9 (21%) and 20 (46%) of the cases, respectively. Column B indicates chromosome bands with the highest frequency of gain or loss within the arm specified in column A. Column C indicates the number and frequency of cases harboring gain or loss in the region specified in column B.