Table 5 Clinicobiologic parameters... | American Society of Hematology

Table 5

Clinicobiologic parameters influencing OS on univariate and multivariate analysis

Parameter	HR	OS, P
Univariate analysis
Age > 65 y	—	.000
Hb < 12 g/dL	—	.004
β₂-Microglobulin level > 3 mg/L	—	.008
More than or equal to 2 cytogenetic alterations	—	.038
Alterations at 14q	—	.013
14q deletions	—	.007
TP53 deletion (FISH)	—	.035
Lymphocytes < 4 × 10⁹/L	—	.027
Platelet count < 100 × 10⁹	—	.092
CD5 PB expression	—	.898
IGHV mutational status	—	.301
Karyotype, abnormal versus normal	—	.302
7q deletion	—	.494
+3/+3q	—	.379
6q deletion	—	.307
Multivariate analysis
Age > 65 y	3.102	.000
Hb < 12 g/dL	1.915	.014

Parameter	HR	OS, P
Univariate analysis
Age > 65 y	—	.000
Hb < 12 g/dL	—	.004
β₂-Microglobulin level > 3 mg/L	—	.008
More than or equal to 2 cytogenetic alterations	—	.038
Alterations at 14q	—	.013
14q deletions	—	.007
TP53 deletion (FISH)	—	.035
Lymphocytes < 4 × 10⁹/L	—	.027
Platelet count < 100 × 10⁹	—	.092
CD5 PB expression	—	.898
IGHV mutational status	—	.301
Karyotype, abnormal versus normal	—	.302
7q deletion	—	.494
+3/+3q	—	.379
6q deletion	—	.307
Multivariate analysis
Age > 65 y	3.102	.000
Hb < 12 g/dL	1.915	.014

HR indicates hazard risk; —, not applicable; and PB, peripheral blood.