Table 2 Time course of platelet count... | American Society of Hematology

Table 2

Time course of platelet count and bleeding tendency in patients MYH9-RD treated with eltrombopag

Patient no./mutation/splenectomy	References	Visit day	Platelets × 10⁹/L		WHO bleeding scale
Patient no./mutation/splenectomy	References	Visit day	Microscopy	Cell counter	WHO bleeding scale
1/p.N93K/Yes	2,4,19	Baseline	13	not given	2
		T 21	38	24	2
		T 42	120	33	0
		PT +15	15	4	2
		PT +30	16	2	2
2/p.R702C/No	2,4	Baseline	13	2	2
		T 21	22	5	2
		T 42	26	6	2
		PT +15	13	5	2
		PT +30	not available	not available	not available
3/p.D1424H/No	2,4	Baseline	48	15	2
		T 21	159	48	0
		PT +15	81	21	0
		PT +30	22	10	2
4/p.R1933X/No	4	Baseline	24	7	2
		T 21	40	24	0
		T 42	48	47	0
		PT +15	44	11	0
		PT +30	not available	not available	not available
5/p.R1165C/Yes	2,4,19	Baseline	45	12	2
		T 21	194	56	0
		PT +15	146	33	0
		PT +30	59	12	0
6/p.D1424H/No	present report	Baseline	14	6	0
		T 21	40	11	0
		T 42	52	17	0
		PT +15	32	6	0
		PT +30	15	4	0
7/p.D1424H/No	present report	Baseline	34	13	0
		T 21	86	27	0
		T 42	84	19	0
		PT +15	62	17	0
		PT +30	40	15	0
8/p.E1066_ A1072del/Yes	2,4	Baseline	50	33	1
		T 21	176	80	0
		PT +15	121	29	0
		PT +30	72	20	0
9/p.D1447V/No	4	Baseline	40	20	1
		T 21	87	59	0
		T 42	111	66	0
		PT +15	62	28	0
		PT +30	66	34	0
10/p.D1447V/No	4	Baseline	49	37	1
		T 21	117	44	0
		T 42	140	47	0
		PT +15	88	31	0
		PT +30	65	23	0
11/p.S96L/Yes	4	Baseline	26	24	2
		T 21	113	32	0
		T 42	114	33	0
		PT +15	63	24	0
		PT +30	34	15	1
12/p.S96L/No	4	Baseline	19	16	1
		T 21	26	23	0
		T 42	33	26	2
		PT +15	20	13	0
		PT +30	18	25	1

Patient no./mutation/splenectomy	References	Visit day	Platelets × 10⁹/L		WHO bleeding scale
Patient no./mutation/splenectomy	References	Visit day	Microscopy	Cell counter	WHO bleeding scale
1/p.N93K/Yes	2,4,19	Baseline	13	not given	2
		T 21	38	24	2
		T 42	120	33	0
		PT +15	15	4	2
		PT +30	16	2	2
2/p.R702C/No	2,4	Baseline	13	2	2
		T 21	22	5	2
		T 42	26	6	2
		PT +15	13	5	2
		PT +30	not available	not available	not available
3/p.D1424H/No	2,4	Baseline	48	15	2
		T 21	159	48	0
		PT +15	81	21	0
		PT +30	22	10	2
4/p.R1933X/No	4	Baseline	24	7	2
		T 21	40	24	0
		T 42	48	47	0
		PT +15	44	11	0
		PT +30	not available	not available	not available
5/p.R1165C/Yes	2,4,19	Baseline	45	12	2
		T 21	194	56	0
		PT +15	146	33	0
		PT +30	59	12	0
6/p.D1424H/No	present report	Baseline	14	6	0
		T 21	40	11	0
		T 42	52	17	0
		PT +15	32	6	0
		PT +30	15	4	0
7/p.D1424H/No	present report	Baseline	34	13	0
		T 21	86	27	0
		T 42	84	19	0
		PT +15	62	17	0
		PT +30	40	15	0
8/p.E1066_ A1072del/Yes	2,4	Baseline	50	33	1
		T 21	176	80	0
		PT +15	121	29	0
		PT +30	72	20	0
9/p.D1447V/No	4	Baseline	40	20	1
		T 21	87	59	0
		T 42	111	66	0
		PT +15	62	28	0
		PT +30	66	34	0
10/p.D1447V/No	4	Baseline	49	37	1
		T 21	117	44	0
		T 42	140	47	0
		PT +15	88	31	0
		PT +30	65	23	0
11/p.S96L/Yes	4	Baseline	26	24	2
		T 21	113	32	0
		T 42	114	33	0
		PT +15	63	24	0
		PT +30	34	15	1
12/p.S96L/No	4	Baseline	19	16	1
		T 21	26	23	0
		T 42	33	26	2
		PT +15	20	13	0
		PT +30	18	25	1

MYH9 mutations and previous splenectomy are reported, as well as previous paper(s) reporting that patient.

T indicates treatment day; PT, posttreatment day; and WHO, World Health Organization.