Baseline characteristics of patients
| Characteristic . | . |
|---|---|
| Sex, n (%) | |
| Female | 7 (58) |
| Male | 5 (42) |
| Age, y | |
| Mean | 35.0 |
| SD | 14.3 |
| Weight, kg | |
| Mean | 70.2 |
| SD | 13.2 |
| Platelet count by cell counter, ×109/L | |
| Mean | 16.5 |
| SD | 10.5 |
| Platelet count by microscopy, ×109/L | |
| Mean | 31.2 |
| SD | 14.8 |
| Mean platelet volume, fL | |
| Mean | 15.1 |
| SD | 4.3 |
| Mean platelet diameter,* μm | |
| Mean | 5.1 |
| SD | 1.1 |
| WHO bleeding scale, n (%) | |
| Grade 0 | 2 (17) |
| Grade 1 | 4 (33) |
| Grade 2 | 6 (50) |
| Serum thrombopoietin level,†pg/mL | |
| Median | 43.7 |
| IQR | 7.3-78.2 |
| Mean time since previous splenectomy, n (%) | |
| Yes | 4 (33) [26.2 y] |
| No | 8 (67) |
| Proteinuric nephropathy,‡n (%) | |
| Yes | 3 (25) |
| No | 9 (75) |
| Sensorineural hearing loss,§n (%) | |
| Yes | 9 (75) |
| No | 3 (25) |
| Cataract, n (%) | |
| Yes | 1 (8) |
| No | 11 (92) |
| Position of MYH9 mutation, n (%) | |
| Motor domain | 4 (33) |
| Tail domain | 8 (67) |
| Characteristic . | . |
|---|---|
| Sex, n (%) | |
| Female | 7 (58) |
| Male | 5 (42) |
| Age, y | |
| Mean | 35.0 |
| SD | 14.3 |
| Weight, kg | |
| Mean | 70.2 |
| SD | 13.2 |
| Platelet count by cell counter, ×109/L | |
| Mean | 16.5 |
| SD | 10.5 |
| Platelet count by microscopy, ×109/L | |
| Mean | 31.2 |
| SD | 14.8 |
| Mean platelet volume, fL | |
| Mean | 15.1 |
| SD | 4.3 |
| Mean platelet diameter,* μm | |
| Mean | 5.1 |
| SD | 1.1 |
| WHO bleeding scale, n (%) | |
| Grade 0 | 2 (17) |
| Grade 1 | 4 (33) |
| Grade 2 | 6 (50) |
| Serum thrombopoietin level,†pg/mL | |
| Median | 43.7 |
| IQR | 7.3-78.2 |
| Mean time since previous splenectomy, n (%) | |
| Yes | 4 (33) [26.2 y] |
| No | 8 (67) |
| Proteinuric nephropathy,‡n (%) | |
| Yes | 3 (25) |
| No | 9 (75) |
| Sensorineural hearing loss,§n (%) | |
| Yes | 9 (75) |
| No | 3 (25) |
| Cataract, n (%) | |
| Yes | 1 (8) |
| No | 11 (92) |
| Position of MYH9 mutation, n (%) | |
| Motor domain | 4 (33) |
| Tail domain | 8 (67) |
SD indicates standard deviation; and IQR, interquartile range.
Normal value calculated in 40 healthy subjects was 2.6 μm (SD 0.32).
Value determined in 40 healthy controls was 14.6 pg/mL (IQR 7.0-23.2).
Defined by 24 hours of proteinuria of 0.5 g or more, in at least 2 consecutive examinations, in the absence of any other possible cause of proteinuria.
As determined by audiometric examination.