Expression of lineage-specific markers in the spleens of uninfected (control) and F-MuLV–infected H/H and Tr/Tr mice
| Mouse/treatment . | Marker . | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| c-Kit . | Sca1 . | Ter-119 . | B220/CD19 . | CD4 . | CD8 . | Gr-1 . | Mac-1 . | 33D1 . | |
| H/H | |||||||||
| Control | 1.9 ± 1.4 | 8.5 ± 5 | 5.8 ± 3.9 | 38.8 ± 3.15 | 14 ± 3.9 | 10.4 ± 1.8 | 2.9 ± 0.4 | 3.2 ± 0.8 | 30.2 ± 5.0 |
| F-MuLV | 50.2 ± 24.8* | 5.0 ± 2.8 | 22.0 ± 7.5 | 1.95 ± 0.5 | 2.4 ± 0.7* | 1.25 ± 0.4* | 0.8 ± 0.3* | 0.9 ± 0.4* | 5.9 ± 1.1* |
| Tr/Tr | |||||||||
| Control | 1.7 ± 0.7 | 35.2 ± 12.9 | 17.7 ± 3.2 | 45.95 ± 3.2 | 14.4 ± 5.4 | 11.6 ± 0.95 | 4.2 ± 0.9 | 4.6 ± 0.5 | 28.1 ± 3.9 |
| F-MuLV | 14.1 ± 12.4* | 26.9 ± 12.4 | 30.7 ± 13.9 | 11.5 ± 2.0 | 10.0 ± 2.7 | 8.0 ± 3.4 | 7.9 ± 4.2 | 6.2 ± 1.5 | 15.8 ± 1.7 |
| Mouse/treatment . | Marker . | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| c-Kit . | Sca1 . | Ter-119 . | B220/CD19 . | CD4 . | CD8 . | Gr-1 . | Mac-1 . | 33D1 . | |
| H/H | |||||||||
| Control | 1.9 ± 1.4 | 8.5 ± 5 | 5.8 ± 3.9 | 38.8 ± 3.15 | 14 ± 3.9 | 10.4 ± 1.8 | 2.9 ± 0.4 | 3.2 ± 0.8 | 30.2 ± 5.0 |
| F-MuLV | 50.2 ± 24.8* | 5.0 ± 2.8 | 22.0 ± 7.5 | 1.95 ± 0.5 | 2.4 ± 0.7* | 1.25 ± 0.4* | 0.8 ± 0.3* | 0.9 ± 0.4* | 5.9 ± 1.1* |
| Tr/Tr | |||||||||
| Control | 1.7 ± 0.7 | 35.2 ± 12.9 | 17.7 ± 3.2 | 45.95 ± 3.2 | 14.4 ± 5.4 | 11.6 ± 0.95 | 4.2 ± 0.9 | 4.6 ± 0.5 | 28.1 ± 3.9 |
| F-MuLV | 14.1 ± 12.4* | 26.9 ± 12.4 | 30.7 ± 13.9 | 11.5 ± 2.0 | 10.0 ± 2.7 | 8.0 ± 3.4 | 7.9 ± 4.2 | 6.2 ± 1.5 | 15.8 ± 1.7 |
Flow cytometric analysis of spleen cells from uninfected control (n = 8) and F-MuLV–infected (n = 9) Tr/Tr and H/H mice. Splenocytes were stained with cKit, Sca1, Ter119, B220, CD19, CD4, CD8, Gr-1, Mac-1, and 33D1. The numbers represent the percentage of stained cells. Values represent the mean ± SEM.
P < .05.