In vivo reversion of the genetic mutation introduced in the 30KO and HBZKO viruses in the tissues of the infected macaques
Animal no. . | Weeks after infection . | Clones with mutated viral sequence/no. of clones sequenced . |
---|---|---|
p30 KO | ||
P064 (BM) | 46 | 0/10 |
P011 (PBMC) | 12 | 0/10 |
pHBZ KO | ||
P068 (BM) | 46 | 0/10 |
M902 (PBMC) | 12 | 1/6 |
P069 (PBMC) | 4 | 10/10 |
8 | 9/10 | |
10 | 3/10 | |
12 | 1/10 |
Animal no. . | Weeks after infection . | Clones with mutated viral sequence/no. of clones sequenced . |
---|---|---|
p30 KO | ||
P064 (BM) | 46 | 0/10 |
P011 (PBMC) | 12 | 0/10 |
pHBZ KO | ||
P068 (BM) | 46 | 0/10 |
M902 (PBMC) | 12 | 1/6 |
P069 (PBMC) | 4 | 10/10 |
8 | 9/10 | |
10 | 3/10 | |
12 | 1/10 |
BM indicates bone marrow.