Copies of HTLV-1 integrase DNA in blood and tissues/106 cells in the infected macaques
| . | PBMC . | LN . | BM . | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Weeks after inoculation . | Weeks after inoculation . | Weeks after inoculation . | ||||||||
| −4 . | 2 . | 4 . | 8 . | 10 . | 12 . | 14 . | 12 . | 46 . | 46 . | |
| p12KO | ||||||||||
| P065 | — | — | — | — | — | — | — | — | — | — |
| P067 | — | — | — | 45 | — | — | — | — | — | — |
| M903 | — | — | — | — | — | — | 14 | — | — | — |
| M045 | — | — | — | — | — | — | — | — | — | — |
| p30KO | ||||||||||
| P063 | — | — | — | — | — | — | — | — | — | — |
| P064 | — | — | — | — | — | — | 13 | — | — | 44 |
| P011 | — | — | — | — | 25 | 87 | — | — | — | — |
| M901 | — | — | — | — | — | 22 | — | — | — | — |
| pHBZKO | ||||||||||
| P068 | — | — | — | — | — | 25 | — | — | — | 42 |
| P069 | — | 16 | 49 | 93 | 91 | 116 | 38 | 27.35 | — | — |
| M900 | — | — | — | — | — | 11 | — | — | — | — |
| M902 | — | — | — | — | — | 40 | — | — | — | — |
| Controls | ||||||||||
| P062 | — | — | — | — | — | — | — | — | — | — |
| M895 | — | — | — | — | — | — | — | — | — | — |
| . | PBMC . | LN . | BM . | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Weeks after inoculation . | Weeks after inoculation . | Weeks after inoculation . | ||||||||
| −4 . | 2 . | 4 . | 8 . | 10 . | 12 . | 14 . | 12 . | 46 . | 46 . | |
| p12KO | ||||||||||
| P065 | — | — | — | — | — | — | — | — | — | — |
| P067 | — | — | — | 45 | — | — | — | — | — | — |
| M903 | — | — | — | — | — | — | 14 | — | — | — |
| M045 | — | — | — | — | — | — | — | — | — | — |
| p30KO | ||||||||||
| P063 | — | — | — | — | — | — | — | — | — | — |
| P064 | — | — | — | — | — | — | 13 | — | — | 44 |
| P011 | — | — | — | — | 25 | 87 | — | — | — | — |
| M901 | — | — | — | — | — | 22 | — | — | — | — |
| pHBZKO | ||||||||||
| P068 | — | — | — | — | — | 25 | — | — | — | 42 |
| P069 | — | 16 | 49 | 93 | 91 | 116 | 38 | 27.35 | — | — |
| M900 | — | — | — | — | — | 11 | — | — | — | — |
| M902 | — | — | — | — | — | 40 | — | — | — | — |
| Controls | ||||||||||
| P062 | — | — | — | — | — | — | — | — | — | — |
| M895 | — | — | — | — | — | — | — | — | — | — |
LN indicates lymph node; BM, bone marrow; and —, viral DNA not detectable.