Grade of severity and management of patients with ITP
| Bleeding/quality of life . | Management approach . |
|---|---|
| Grade 1. Minor bleeding, few petechiae (≤ 100 total) and/or ≤ 5 small bruises (≤ 3-cm diameter); no mucosal bleeding | Consent for observation |
| Grade 2. Mild bleeding, many petechiae (> 100 total) and/or > 5 large bruises (> 3-cm diameter); no mucosal bleeding | Consent for observation or for treatment in selected children |
| Grade 3. Moderate bleeding, overt mucosal bleeding, troublesome lifestyle | Intervention to reach grade 1/2 in selected children |
| Grade 4. Mucosal bleeding or suspected internal hemorrhage | Intervention |
| Bleeding/quality of life . | Management approach . |
|---|---|
| Grade 1. Minor bleeding, few petechiae (≤ 100 total) and/or ≤ 5 small bruises (≤ 3-cm diameter); no mucosal bleeding | Consent for observation |
| Grade 2. Mild bleeding, many petechiae (> 100 total) and/or > 5 large bruises (> 3-cm diameter); no mucosal bleeding | Consent for observation or for treatment in selected children |
| Grade 3. Moderate bleeding, overt mucosal bleeding, troublesome lifestyle | Intervention to reach grade 1/2 in selected children |
| Grade 4. Mucosal bleeding or suspected internal hemorrhage | Intervention |
Modified from Buchanan and Adix181 ; Bolton-Maggs and Moon174 ; Imbach et al.171