Table 3

Multivariate analysis of factors associated with malaria parasitemia at OPD clinic and during hospitalization in patients with SCA

OR (95% CI)P
OPD clinic   
    Age, y 1.00 (0.951-1.06) .916 
    Febrile (temperature > 37.5°C) 3.30 (0.97-11.29) .057 
    Peripheral oxygen saturation, % 1.07 (0.94-1.21) .300 
    Hepatomegaly 2.95 (0.85-10.18) .087 
    Splenomegaly 1.09 (0.40-2.95) .867 
    High WBC count (> 17.7 × 109/L) 3.29 (1.50-7.18) .003 
    Hemoglobin, g/dL* 0.79 (0.59-1.047) .101 
Hospitalization   
    Age, y 1.04 (0.99-1.09) .088 
    Severe anemia Hb < 5 g/dL) 3.46 (1.27-9.45) .016 
    Raised MCV (> 93 fL) 2.22 (0.73-6.72) .158 
    Reticulocyte count, % 1.04 (0.97-1.10) .264 
    Raised AST level (> 97.2 IU/L) 3.41 (1.23-9.45) .018 
    Death 0.49 (0.04-5.74) .573 
OR (95% CI)P
OPD clinic   
    Age, y 1.00 (0.951-1.06) .916 
    Febrile (temperature > 37.5°C) 3.30 (0.97-11.29) .057 
    Peripheral oxygen saturation, % 1.07 (0.94-1.21) .300 
    Hepatomegaly 2.95 (0.85-10.18) .087 
    Splenomegaly 1.09 (0.40-2.95) .867 
    High WBC count (> 17.7 × 109/L) 3.29 (1.50-7.18) .003 
    Hemoglobin, g/dL* 0.79 (0.59-1.047) .101 
Hospitalization   
    Age, y 1.04 (0.99-1.09) .088 
    Severe anemia Hb < 5 g/dL) 3.46 (1.27-9.45) .016 
    Raised MCV (> 93 fL) 2.22 (0.73-6.72) .158 
    Reticulocyte count, % 1.04 (0.97-1.10) .264 
    Raised AST level (> 97.2 IU/L) 3.41 (1.23-9.45) .018 
    Death 0.49 (0.04-5.74) .573 

WBC indicates white blood cell; Hb, hemoglobin; MCV, mean corpuscular volume; and AST, aspartate transaminase.

*

Severe anemia in model (OR, 1.96; 95%CI, 0.54-7.12; P = .305).

Hb in the model (OR, 0.81; 95% CI, 0.61-1.07; P = .137).

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