PRs for MGUS in relation to sex, age at exposure, and distance from the hypocenter in participants with information of exposure distance
. | All . | Age at exposure < 20 y . | Age at exposure ≥ 20 y . | |||
---|---|---|---|---|---|---|
PR (95% CI) . | P . | PR (95% CI) . | P . | PR (95% CI) . | P . | |
Univariate analysis | ||||||
Sex | ||||||
Male | 1.7 (1.5-1.9) | < .001 | 1.8 (1.5-2.1) | < .001 | 2.0 (1.5-2.5) | < .001 |
Female | Referent | Referent | Referent | |||
Age at exposure | ||||||
Per y | 1.4 (1.3-1.5) | < .001 | 1.1 (1.1 - 1.1) | <.001 | 1.0 (1.0-1.1) | .001 |
Per 5 y | 1.2 (1.1-1.2) | < .001 | 1.4 (1.3 -1.5) | <.001 | 1.2 (1.1-1.3) | .001 |
Age at exposure group | ||||||
30 y or older | 2.6 (2.0-3.3) | < .001 | 1.3 (1.0-1.7) | .02 | ||
20 to < 30 y | 2.0 (1.6-2.4) | < .001 | Referent | |||
10 to < 20 y | 1.8 (1.5-2.2) | < .001 | 1.8 (1.5-2.2) | <.001 | ||
< 10 y | Referent | Referent | ||||
Exposure distance group | ||||||
< 1.5 km | 1.3 (1.0-1.7) | .02 | 1.7 (1.3-2.3) | < .001 | 0.7 (0.4-1.2) | .2 |
1.5 to < 3.0 km | 1.0 (0.8-1.1) | .7 | 1.1 (0.9-1.3) | .5 | 0.8 (0.6-1.0) | .1 |
3.0 to 10.0 km | Referent | Referent | ||||
Multivariate analysis | ||||||
Male sex | 1.9 (1.6-2.3) | < .001 | 1.9 (1.5-2.4) | < .001 | ||
Age at exposure per 5 y | 1.4 (1.3-1.5) | < .001 | 1.1 (1.0-1.2) | .03 | ||
Exposure distance group | ||||||
< 1.5 km | 1.4 (1.1-1.9) | .02 | 0.6 (0.4-1.1) | .1 | ||
1.5 to < 3.0 km | 1.0 (0.8-1.2) | .9 | 0.8 (0.6-1.0) | .1 | ||
3.0 to 10.0 km | Referent | Referent |
. | All . | Age at exposure < 20 y . | Age at exposure ≥ 20 y . | |||
---|---|---|---|---|---|---|
PR (95% CI) . | P . | PR (95% CI) . | P . | PR (95% CI) . | P . | |
Univariate analysis | ||||||
Sex | ||||||
Male | 1.7 (1.5-1.9) | < .001 | 1.8 (1.5-2.1) | < .001 | 2.0 (1.5-2.5) | < .001 |
Female | Referent | Referent | Referent | |||
Age at exposure | ||||||
Per y | 1.4 (1.3-1.5) | < .001 | 1.1 (1.1 - 1.1) | <.001 | 1.0 (1.0-1.1) | .001 |
Per 5 y | 1.2 (1.1-1.2) | < .001 | 1.4 (1.3 -1.5) | <.001 | 1.2 (1.1-1.3) | .001 |
Age at exposure group | ||||||
30 y or older | 2.6 (2.0-3.3) | < .001 | 1.3 (1.0-1.7) | .02 | ||
20 to < 30 y | 2.0 (1.6-2.4) | < .001 | Referent | |||
10 to < 20 y | 1.8 (1.5-2.2) | < .001 | 1.8 (1.5-2.2) | <.001 | ||
< 10 y | Referent | Referent | ||||
Exposure distance group | ||||||
< 1.5 km | 1.3 (1.0-1.7) | .02 | 1.7 (1.3-2.3) | < .001 | 0.7 (0.4-1.2) | .2 |
1.5 to < 3.0 km | 1.0 (0.8-1.1) | .7 | 1.1 (0.9-1.3) | .5 | 0.8 (0.6-1.0) | .1 |
3.0 to 10.0 km | Referent | Referent | ||||
Multivariate analysis | ||||||
Male sex | 1.9 (1.6-2.3) | < .001 | 1.9 (1.5-2.4) | < .001 | ||
Age at exposure per 5 y | 1.4 (1.3-1.5) | < .001 | 1.1 (1.0-1.2) | .03 | ||
Exposure distance group | ||||||
< 1.5 km | 1.4 (1.1-1.9) | .02 | 0.6 (0.4-1.1) | .1 | ||
1.5 to < 3.0 km | 1.0 (0.8-1.2) | .9 | 0.8 (0.6-1.0) | .1 | ||
3.0 to 10.0 km | Referent | Referent |