Table 1

Summary of SIV insertion site characteristics versus random in silico–generated integration datasets

All SIV, n = 519, no. (%)Matching randoms, %P vs randoms
Sites within a gene 392 (75.5) 32.9 < .001 
Sites within a CpG island or within a 1-kb window of CpG island 1 (0.2) 1.0 .040 
Distribution of sites relative to gene density within 1-Mb window    
            0-10 genes 33.3 79.4 < .001 
            11-20 genes 29.5 15.5 < .001 
            More than 21 genes 37.2 5.1 < .001 
All SIV, n = 519, no. (%)Matching randoms, %P vs randoms
Sites within a gene 392 (75.5) 32.9 < .001 
Sites within a CpG island or within a 1-kb window of CpG island 1 (0.2) 1.0 .040 
Distribution of sites relative to gene density within 1-Mb window    
            0-10 genes 33.3 79.4 < .001 
            11-20 genes 29.5 15.5 < .001 
            More than 21 genes 37.2 5.1 < .001 
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