EpoR mRNA and protein level comparison for positive and negative control cells, the 5 highest EpoR protein-producing cell lines, and the MCF-7 cell line
| Tumor cell line . | Tissue . | EpoR mRNA, % of control . | EpoR protein, dimers/cell . |
|---|---|---|---|
| UT-7/Epo | Megakaryoblastic leukemia | 100 | 30 000-100 000 |
| Erythroid progenitor cells | Differentiated CD34+ PBMCs | 37-52 | 8000-16 000 |
| OCIM-1 | Erythroleukemia | 10.3 | 8000-16 000 |
| NCI-H510A | Lung, small cell | 10.6 | 1600-3200 |
| DMS-79 | Lung, small cell | 8.6 | 1600-3200 |
| NCI-H1299 | Lung, non–small cell | 5.2 | 1600-3200 |
| NCI-H661 | Lung, non–small cell | 4.2 | 1600-3200 |
| A2780 | Ovary | 4.5 | 400-1600 |
| COL0677 | Colon | 1.4 | Undetectable (< 25) |
| 769-P | Kidney | 0.2 | Undetectable (< 25) |
| MCF-7 | Breast | 1.2 | 25-100 |
| Tumor cell line . | Tissue . | EpoR mRNA, % of control . | EpoR protein, dimers/cell . |
|---|---|---|---|
| UT-7/Epo | Megakaryoblastic leukemia | 100 | 30 000-100 000 |
| Erythroid progenitor cells | Differentiated CD34+ PBMCs | 37-52 | 8000-16 000 |
| OCIM-1 | Erythroleukemia | 10.3 | 8000-16 000 |
| NCI-H510A | Lung, small cell | 10.6 | 1600-3200 |
| DMS-79 | Lung, small cell | 8.6 | 1600-3200 |
| NCI-H1299 | Lung, non–small cell | 5.2 | 1600-3200 |
| NCI-H661 | Lung, non–small cell | 4.2 | 1600-3200 |
| A2780 | Ovary | 4.5 | 400-1600 |
| COL0677 | Colon | 1.4 | Undetectable (< 25) |
| 769-P | Kidney | 0.2 | Undetectable (< 25) |
| MCF-7 | Breast | 1.2 | 25-100 |
PBMCs indicates peripheral blood mononuclear cells.