Results of focus formation assays comparing wild-type RAS and various RAS mutations
| Gene/allele . | Average foci per plate . | Standard error . | Paired t test with WT, P . |
|---|---|---|---|
| None | 0 | 0 | — |
| Empty vector | 0 | 0 | — |
| NRAS | |||
| WT | 25 | 2 | — |
| G12D | 1250 | 101 | .007 |
| G60E | 698 | 20 | .001 |
| KRAS | |||
| WT | 26 | 2 | — |
| G12D | 957 | 53 | .003 |
| T74P | 659 | 54 | .007 |
| A146T | 1012 | 48 | .002 |
| Gene/allele . | Average foci per plate . | Standard error . | Paired t test with WT, P . |
|---|---|---|---|
| None | 0 | 0 | — |
| Empty vector | 0 | 0 | — |
| NRAS | |||
| WT | 25 | 2 | — |
| G12D | 1250 | 101 | .007 |
| G60E | 698 | 20 | .001 |
| KRAS | |||
| WT | 26 | 2 | — |
| G12D | 957 | 53 | .003 |
| T74P | 659 | 54 | .007 |
| A146T | 1012 | 48 | .002 |