Table 3 High macrophage turnover in... | American Society of Hematology

Table 3

High macrophage turnover in mesenteric lymph node of SIV-infected (AIDS) monkey

Animal/area	Total		CD163⁺ cells (macrophage)
Animal/area	BrdU⁺	TUNEL⁺	Total	BrdU⁺	TUNEL⁺	TUNEL⁺BrdU⁺
Uninfected (3.0%)*
Sinus	73.8 ± 26.6‡	6.6 ± 2.3	40.8 ± 2.9	2.0 ± 1.6	0.4 ± 0.5	0
Follicle	90.8 ± 25.1	7.4 ± 3.9	37.0 ± 18.4	2.0 ± 1.4	0.4 ± 0.5	0.2 ± 0.4
Infected (45.3%)
Sinus	189.0 ± 25.1	27.6 ± 7.8	194.6 ± 11.0	33.6 ± 3.5	11.0 ± 1.4	2.0 ± 1.0
Follicle	169.2 ± 87.5	33.8 ± 11.9	162.4 ± 43.2	27.0 ± 7.0	10.2 ± 1.8	1.0 ± 0.7
P†
Sinus	.0001‖	.0004	< .0001	< .0001	< .0001	na§
Follicle	.0904‖	.0015	.0003	< .0001	< .0001	.0650‖

Animal/area	Total		CD163⁺ cells (macrophage)
Animal/area	BrdU⁺	TUNEL⁺	Total	BrdU⁺	TUNEL⁺	TUNEL⁺BrdU⁺
Uninfected (3.0%)*
Sinus	73.8 ± 26.6‡	6.6 ± 2.3	40.8 ± 2.9	2.0 ± 1.6	0.4 ± 0.5	0
Follicle	90.8 ± 25.1	7.4 ± 3.9	37.0 ± 18.4	2.0 ± 1.4	0.4 ± 0.5	0.2 ± 0.4
Infected (45.3%)
Sinus	189.0 ± 25.1	27.6 ± 7.8	194.6 ± 11.0	33.6 ± 3.5	11.0 ± 1.4	2.0 ± 1.0
Follicle	169.2 ± 87.5	33.8 ± 11.9	162.4 ± 43.2	27.0 ± 7.0	10.2 ± 1.8	1.0 ± 0.7
P†
Sinus	.0001‖	.0004	< .0001	< .0001	< .0001	na§
Follicle	.0904‖	.0015	.0003	< .0001	< .0001	.0650‖

Percentages of BrdU⁺ monocytes in blood are indicated.

Data were analyzed for statistical significance by the unpaired t test.

Each value represents mean ± SD of the cell number per area obtained from 5 randomly selected areas.

na indicates not applicable.

Not significant (P > .05).