Table 5

Clinical and laboratory data in donors with a poor mobilization response to G-CSF

Post–G-CSF CD34+ cell count/μLNSex, female/male, %Ethnicity W/B/H/AP, %G-CSF dose, μg/kg per day 10/16, %Weight, kgHeight, cmBMI, kg/m2Estimated body fat, %Age, yPre–G-CSF platelet count, ×109/LPre–G-CSF MNC, ×109/LTotal G-CSF, μg/dPrior lymphapheresis, yes/no (%)
All donors 639 49/51 64/12/18/6 96/4 79 170 27.1 28.7 40.4 256 2.43 808 26/74 
Less than 30 73 70/30 78/3/14/5 100/0 68 169 23.4 25.8 41.7 236 2.21 688 22/78 
More than or equal to 30 566 48/52 64/13/19/6 95/5 80 171 27.5 29.1 40.3 259 2.46 822 26/74 
P  <.001 .01 .1 <.001 .12 <.001 <.001 .3 .002 .002 <.001 .4 
Less than 20 29 74/26 81/4/15/0 100/0 67 170 22.9 24.6 41.9 226 1.96 663 15/85 
More than or equal to 20 610 49/51 64/12/18/6 95/5 79 170 27.1 28.9 40.4 260 2.45 812 26/74 
P  .02 .08 .6 <.001 .4 <.001 <.001 .4 .006 <.001 <.001 .3 
Post–G-CSF CD34+ cell count/μLNSex, female/male, %Ethnicity W/B/H/AP, %G-CSF dose, μg/kg per day 10/16, %Weight, kgHeight, cmBMI, kg/m2Estimated body fat, %Age, yPre–G-CSF platelet count, ×109/LPre–G-CSF MNC, ×109/LTotal G-CSF, μg/dPrior lymphapheresis, yes/no (%)
All donors 639 49/51 64/12/18/6 96/4 79 170 27.1 28.7 40.4 256 2.43 808 26/74 
Less than 30 73 70/30 78/3/14/5 100/0 68 169 23.4 25.8 41.7 236 2.21 688 22/78 
More than or equal to 30 566 48/52 64/13/19/6 95/5 80 171 27.5 29.1 40.3 259 2.46 822 26/74 
P  <.001 .01 .1 <.001 .12 <.001 <.001 .3 .002 .002 <.001 .4 
Less than 20 29 74/26 81/4/15/0 100/0 67 170 22.9 24.6 41.9 226 1.96 663 15/85 
More than or equal to 20 610 49/51 64/12/18/6 95/5 79 170 27.1 28.9 40.4 260 2.45 812 26/74 
P  .02 .08 .6 <.001 .4 <.001 <.001 .4 .006 <.001 <.001 .3 
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