The 10 most significant up- and down-regulated genes after treatment with IGF-1 for 12 hours
| Gene name . | Abbreviation . | Process . |
|---|---|---|
| Genes significantly up-regulated | ||
| Cystathionase (cystathionine gamma-lyase) | Cth | Amino acid/nucleotide synthesis |
| Dynactin 5 | Dctn5 | Transport |
| Glycogen synthase 3, brain | Gys3 | Glucose uptake/ metabolism |
| Squalene epoxidase | Sqle | Lipogenesis |
| Tspy-like 4 | Tspyl4 | Chromatin assembly |
| 3-hydroxy-3-methylglutaryl-coenzyme A synthase 1 | Hmgcs1 | Lipogenesis |
| Low-density lipoprotein receptor | Ldlr | Lipogenesis |
| Solute carrier family 2 (facilitated glucose transporter), member 1 | Slc2a1 | Nutrient uptake |
| Stanniocalcin 2 | Stc2 | Signaling |
| Translocase of inner mitochondrial membrane 8 homolog a (yeast) | Timm8a | Glucose uptake/metabolism |
| Genes significantly down-regulated | ||
| Yippee-like3 | Ypel3 | Apoptosis |
| Transcription factor 2 | Tcf2 | Transcription/ RNA processing |
| Hypothetical protein R07G3.7a | 2310001H12Rik | Unknown |
| F-box only protein 32 | Fbxo32 | Protein modification |
| v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | Erbb3 | Apoptosis |
| Expressed sequence AI661017 | AI661017 | Unknown |
| cDNA sequence BC024760 | BC024760 | Unknown |
| Kelch-like24 | klhl24 | Signaling |
| Interleukin 16 | Il16 | Signaling |
| BCL2-like 11 (apoptosis facilitator) | Bim | Apoptosis |
| Gene name . | Abbreviation . | Process . |
|---|---|---|
| Genes significantly up-regulated | ||
| Cystathionase (cystathionine gamma-lyase) | Cth | Amino acid/nucleotide synthesis |
| Dynactin 5 | Dctn5 | Transport |
| Glycogen synthase 3, brain | Gys3 | Glucose uptake/ metabolism |
| Squalene epoxidase | Sqle | Lipogenesis |
| Tspy-like 4 | Tspyl4 | Chromatin assembly |
| 3-hydroxy-3-methylglutaryl-coenzyme A synthase 1 | Hmgcs1 | Lipogenesis |
| Low-density lipoprotein receptor | Ldlr | Lipogenesis |
| Solute carrier family 2 (facilitated glucose transporter), member 1 | Slc2a1 | Nutrient uptake |
| Stanniocalcin 2 | Stc2 | Signaling |
| Translocase of inner mitochondrial membrane 8 homolog a (yeast) | Timm8a | Glucose uptake/metabolism |
| Genes significantly down-regulated | ||
| Yippee-like3 | Ypel3 | Apoptosis |
| Transcription factor 2 | Tcf2 | Transcription/ RNA processing |
| Hypothetical protein R07G3.7a | 2310001H12Rik | Unknown |
| F-box only protein 32 | Fbxo32 | Protein modification |
| v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | Erbb3 | Apoptosis |
| Expressed sequence AI661017 | AI661017 | Unknown |
| cDNA sequence BC024760 | BC024760 | Unknown |
| Kelch-like24 | klhl24 | Signaling |
| Interleukin 16 | Il16 | Signaling |
| BCL2-like 11 (apoptosis facilitator) | Bim | Apoptosis |