Types of bone marrow progenitors in MxPtch1Δ/Δ mice
| Genotype . | Colonies . | ||||||
|---|---|---|---|---|---|---|---|
| Total . | Granulocyte . | GM . | Macrophage . | Megakaryocyte . | GEMM . | Blast . | |
| +/Δ (n = 3) | 62 ± 12 | 13 ± 6 | 23 ± 8 | 12 ± 2 | 7 ± 3 | 3 ± 2 | 4 ± 2 |
| Δ/Δ (n = 3) | 87 ± 18 | 14 ± 2 | 26 ± 4 | 21 ± 7 | 12 ± 5 | 8 ± 4 | 6 ± 2 |
| Genotype . | Colonies . | ||||||
|---|---|---|---|---|---|---|---|
| Total . | Granulocyte . | GM . | Macrophage . | Megakaryocyte . | GEMM . | Blast . | |
| +/Δ (n = 3) | 62 ± 12 | 13 ± 6 | 23 ± 8 | 12 ± 2 | 7 ± 3 | 3 ± 2 | 4 ± 2 |
| Δ/Δ (n = 3) | 87 ± 18 | 14 ± 2 | 26 ± 4 | 21 ± 7 | 12 ± 5 | 8 ± 4 | 6 ± 2 |
Mean and SD from 3 mice plated in triplicate.
GM indicates granulocyte/macrophage mixed; and GEMM, granulocyte/erythroid/macrophage/megakaryocyte mixed.