Table 2

Overview of reported therapies for primary cutaneous B-cell lymphomas

TherapyReferences
First- and second-line therapies  
    Local radiotherapy 5,21,,,,,,,,,–31,40,45,50,52,,,,,,,,–61,80,81,87,102,,,,,–108  
    Systemic multiagent chemotherapy 21,25,28,–30,40,45,52,53,56,78,,–81,84,85,93,96,104,105,109  
    Systemic rituximab (Mabthera) 34,–36,38,68,,,,,,,,–77,88,,,–92  
    Chorambucil (Leukeran) 23,25,31,39,60,110  
    Excision 5,21,25,28,,,–32,53,–55,60,81,104,111  
    Antibiotics 29,31,45,,–48,112  
    Radiochemotherapy 28,45,52,54,–56,94,95,113  
Investigational therapies  
    IFN-α intralesional 33,46,62,–64,114,–116  
    Rituximab intralesional 34,36,37,65,–67  
    Adenovirus-mediated IFN-γ gene transfer 99,–101  
Anecdotal therapies  
    Photodynamic therapy 117,118  
    Cisplatin intralesional 119  
    Mechlorethamine/ clobetasol 120  
    Topical imiquimod 121,122  
    Topical hexadecylphosphocholine 123  
TherapyReferences
First- and second-line therapies  
    Local radiotherapy 5,21,,,,,,,,,–31,40,45,50,52,,,,,,,,–61,80,81,87,102,,,,,–108  
    Systemic multiagent chemotherapy 21,25,28,–30,40,45,52,53,56,78,,–81,84,85,93,96,104,105,109  
    Systemic rituximab (Mabthera) 34,–36,38,68,,,,,,,,–77,88,,,–92  
    Chorambucil (Leukeran) 23,25,31,39,60,110  
    Excision 5,21,25,28,,,–32,53,–55,60,81,104,111  
    Antibiotics 29,31,45,,–48,112  
    Radiochemotherapy 28,45,52,54,–56,94,95,113  
Investigational therapies  
    IFN-α intralesional 33,46,62,–64,114,–116  
    Rituximab intralesional 34,36,37,65,–67  
    Adenovirus-mediated IFN-γ gene transfer 99,–101  
Anecdotal therapies  
    Photodynamic therapy 117,118  
    Cisplatin intralesional 119  
    Mechlorethamine/ clobetasol 120  
    Topical imiquimod 121,122  
    Topical hexadecylphosphocholine 123  

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