Causes of death in HU and non-HU patients
| Cause of death . | HU patients (13/131 = 9.9%) . | Non-HU patients (49/199 = 24.6%) . |
|---|---|---|
| Liver dysfunction | 1 | 10 |
| Pulmonary hypertension | 8 | 8 |
| Stroke | 3 | 10 |
| Sudden death | 3 | 5 |
| Vasoocclusion crisis | 1 | 6 |
| Acute chest syndrome | 1 | 5 |
| Sepsis | 1 | 1 |
| Heart failure | 2 | 2 |
| Intervention | 1 | 2 |
| Cause of death . | HU patients (13/131 = 9.9%) . | Non-HU patients (49/199 = 24.6%) . |
|---|---|---|
| Liver dysfunction | 1 | 10 |
| Pulmonary hypertension | 8 | 8 |
| Stroke | 3 | 10 |
| Sudden death | 3 | 5 |
| Vasoocclusion crisis | 1 | 6 |
| Acute chest syndrome | 1 | 5 |
| Sepsis | 1 | 1 |
| Heart failure | 2 | 2 |
| Intervention | 1 | 2 |
Causes of death were diagnosed contemporaneously by study staff in 45 of 62 patients who died in the center hospital. In all other patients the cause of death was diagnosed by the respective doctors of the hospitals where the death was happened; no autopsy was performed in these patients.
HU indicates hydroxyurea.