Table 2

Dramatic reduction of hospital admissions, painful crises, and transfusion requirements per year of the study in patients who received HU (data as of June 30, 2008)

Years receiving HUNo. of patients receiving HUHospital admissions per year, mean ± SDPainful crises per year, mean ± SDTransfusion requirements, mean ± SD of red-cell packs per year
Baseline 131 2.11 ± 2.96 7.34 ± 6.50 1.53 ± 5.92 
126 0.03 ± 0.19 0.05 ± 0.22 0.22 ± 0.95 
120 0.04 ± 0.21 0.04 ± 0.20 0.19 ± 0.87 
109 0.04 ± 0.21 0.03 ± 0.18 0.08 ± 1.54 
104 0.01 ± 0.13  
97 0.04 ± 0.19 0.03 ± 0.15 
86 0.02 ± 0.15 
80 0.05 ± 0.20 0.02 ± 0.15 0.03 ± 0.19 
76 0.05 ± 0.22 0.02 ± 0.16 
67 0.07 ± 0.26 0.04 ± 0.20 
10 61 0.05 ± 0.22 
11 56 0.06 ± 0.15 0.01 ± 0.13 0.03 ± 0.18 
12 48 0.06 ± 0.24 0.02 ± 0.14 0.04 ± 0.20 
13 42 0.04 ± 0.21 
14 33 0.06 ± 0.24 0.03 ± 0.17 0.06 ± 0.34 
15 26 0.03 ± 0.19 0.03 ± 0.19 
16 18 0.05 ± 0.23 
17 12 
Years receiving HUNo. of patients receiving HUHospital admissions per year, mean ± SDPainful crises per year, mean ± SDTransfusion requirements, mean ± SD of red-cell packs per year
Baseline 131 2.11 ± 2.96 7.34 ± 6.50 1.53 ± 5.92 
126 0.03 ± 0.19 0.05 ± 0.22 0.22 ± 0.95 
120 0.04 ± 0.21 0.04 ± 0.20 0.19 ± 0.87 
109 0.04 ± 0.21 0.03 ± 0.18 0.08 ± 1.54 
104 0.01 ± 0.13  
97 0.04 ± 0.19 0.03 ± 0.15 
86 0.02 ± 0.15 
80 0.05 ± 0.20 0.02 ± 0.15 0.03 ± 0.19 
76 0.05 ± 0.22 0.02 ± 0.16 
67 0.07 ± 0.26 0.04 ± 0.20 
10 61 0.05 ± 0.22 
11 56 0.06 ± 0.15 0.01 ± 0.13 0.03 ± 0.18 
12 48 0.06 ± 0.24 0.02 ± 0.14 0.04 ± 0.20 
13 42 0.04 ± 0.21 
14 33 0.06 ± 0.24 0.03 ± 0.17 0.06 ± 0.34 
15 26 0.03 ± 0.19 0.03 ± 0.19 
16 18 0.05 ± 0.23 
17 12 

HU indicates hydroxyurea.

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