Patient outcomes
Outcome . | No. of patients = 111 . |
---|---|
Posttransplant admission within 100 days, n (%) | 30 (27.0) |
Posttransplant admission diagnosis, n (%) | |
Febrile, nonneutropenic | 11 (36.7) |
Febrile neutropenia | 8 (26.7) |
Cyclosporine toxicity | 5 (16.7) |
Other* | 6 (20.0) |
Posttransplant admission duration, median days (range) | 3.5 (1-21) |
Cause of death, n (%) | 44 (39.6) |
Disease progression | |
Relapse | 25 (56.8) |
cGVHD | 2 (4.5) |
aGVHD | 1 (2.3) |
Cyclosporine microangiopathy | 1 (2.3) |
Infection (bacterial line infection) | 1 (2.3) |
Cardiac disease | 1 (2.3) |
Cerebrovascular accident | 1 (2.3) |
Patient characteristics at last follow-up, n (%) | |
Alive | 67 (60.4) |
Duration of follow-up | |
1-3 y | 40 (59.7) |
> 3 y | 27 (40.3) |
Karnofsky performance status | |
100% | 46 (68.7) |
90% | 16 (23.9) |
80% | 4 (6.0) |
70% | 1 (1.5) |
Immunosuppression, number of medications | |
No immunosuppression | 46 (68.7) |
1 medication | 13 (19.4) |
2 medications | 5 (7.5) |
3 medications | 3 (4.5) |
Alive, relapse or disease progression | 20 (29.9) |
Disease-free interval, median days (range) | 670 (17-2239) |
Current disease status | |
CR | 13 (65.0) |
PR | 6 (30.0) |
PD | 2 (10.0) |
Outcome . | No. of patients = 111 . |
---|---|
Posttransplant admission within 100 days, n (%) | 30 (27.0) |
Posttransplant admission diagnosis, n (%) | |
Febrile, nonneutropenic | 11 (36.7) |
Febrile neutropenia | 8 (26.7) |
Cyclosporine toxicity | 5 (16.7) |
Other* | 6 (20.0) |
Posttransplant admission duration, median days (range) | 3.5 (1-21) |
Cause of death, n (%) | 44 (39.6) |
Disease progression | |
Relapse | 25 (56.8) |
cGVHD | 2 (4.5) |
aGVHD | 1 (2.3) |
Cyclosporine microangiopathy | 1 (2.3) |
Infection (bacterial line infection) | 1 (2.3) |
Cardiac disease | 1 (2.3) |
Cerebrovascular accident | 1 (2.3) |
Patient characteristics at last follow-up, n (%) | |
Alive | 67 (60.4) |
Duration of follow-up | |
1-3 y | 40 (59.7) |
> 3 y | 27 (40.3) |
Karnofsky performance status | |
100% | 46 (68.7) |
90% | 16 (23.9) |
80% | 4 (6.0) |
70% | 1 (1.5) |
Immunosuppression, number of medications | |
No immunosuppression | 46 (68.7) |
1 medication | 13 (19.4) |
2 medications | 5 (7.5) |
3 medications | 3 (4.5) |
Alive, relapse or disease progression | 20 (29.9) |
Disease-free interval, median days (range) | 670 (17-2239) |
Current disease status | |
CR | 13 (65.0) |
PR | 6 (30.0) |
PD | 2 (10.0) |
CR indicates complete remission; PR, partial remission; and PD, progressive disease.
CMV enteritis, n = 1; arrhythmia, n = 1; chest pain, n = 1; acute GVHD, n = 1; GI bleed, n = 1; RSV infection, n = 1.