Graft cell dose and chimerism
| Characteristics . | N = 111 . | Related donor grafts, n = 61 . | Unrelated donor grafts, n = 50 . |
|---|---|---|---|
| Mean cell dose infused (range) | |||
| CD3 cells × 108/kg | 3.2 (0.02-10) | 2.97 (0.02-6.50) | 3.76 (1.30-10) |
| CD34 cells × 106/kg | 7.3 (1.1-20.5) | 6.65 (2.1-12.8) | 8.02 (1.1-20.5) |
| Chimerism, no. (%) | |||
| Complete chimerism (≥ 95%) | 86 (77.5) | 46 (75.4) | 40 (80.0) |
| Mixed chimerism (5%-94%) | 21 (18.9) | 14 (23.0) | 7 (14.0) |
| Primary graft failure (< 5%) | 4 (3.6) | 1 (1.6) | 3 (6.0) |
| Characteristics . | N = 111 . | Related donor grafts, n = 61 . | Unrelated donor grafts, n = 50 . |
|---|---|---|---|
| Mean cell dose infused (range) | |||
| CD3 cells × 108/kg | 3.2 (0.02-10) | 2.97 (0.02-6.50) | 3.76 (1.30-10) |
| CD34 cells × 106/kg | 7.3 (1.1-20.5) | 6.65 (2.1-12.8) | 8.02 (1.1-20.5) |
| Chimerism, no. (%) | |||
| Complete chimerism (≥ 95%) | 86 (77.5) | 46 (75.4) | 40 (80.0) |
| Mixed chimerism (5%-94%) | 21 (18.9) | 14 (23.0) | 7 (14.0) |
| Primary graft failure (< 5%) | 4 (3.6) | 1 (1.6) | 3 (6.0) |
MRD indicates matched related donor; and MUD, matched unrelated donor.