Representative results of routine and specialized laboratory investigations
| Laboratory investigation . | Patient . | Reference . |
|---|---|---|
| Routine | ||
| Hemoglobin, mmol/L | 9.4 | 8.6-10.7 |
| Erythrocytes, ×1012/L | 4.8 | 4.2-5.5 |
| MCV, fL | 87 | 80-97 |
| Reticulocytes, ×109/L | 25 | 25-120 |
| Creatinine, μmol/L | 84 | 74-120 |
| Creatinine kinase, U/L | 114 | 15-175 |
| γ-glutamyl transferase, U/L | 17 | 15-70 |
| Aspartate aminotransferase, U/L | 29 | 15-45 |
| Alanine aminotransferase, U/L | 21 | 10-50 |
| Lactate dehydrogenase, U/L | 494 | 300-620 |
| Unconjugated bilirubin, μmol/L | 24 | 3-21 |
| Haptoglobin, g/L | < 0.1 | 0.3-2.0 |
| Specialized laboratory investigation | ||
| G6PD activity (U/g Hb) in erythrocytes | 0.8 | 7.1-11.5 |
| PK activity (U/g Hb) in erythrocytes | 7.2 | 6.9-14.5 |
| HK activity (U/g Hb) in erythrocytes | 1.12 | 1.0-1.6 |
| G6PD activity (U/g protein) in leukocytes | 530 | 815-877 |
| Calculated G6PD activity (U/g protein) in muscle cells* | 0.5 | 3-4.7 |
| Km for G6P (μmol/L) in leukocytes | 40 | 55-71 |
| Km for NADP (μmol/L) in leukocytes | 45 | 66-76 |
| Ki value for NADPH (μmol/L) in leukocytes | 153 | 142-159 |
| G6PD activity at pH (range, 6.5-9.0) and elevated temperature (39°C, mimicking increased body temperature) | Normal | Normal |
| Oxidative hemolysis | 1.5% | < 2% |
| Laboratory investigation . | Patient . | Reference . |
|---|---|---|
| Routine | ||
| Hemoglobin, mmol/L | 9.4 | 8.6-10.7 |
| Erythrocytes, ×1012/L | 4.8 | 4.2-5.5 |
| MCV, fL | 87 | 80-97 |
| Reticulocytes, ×109/L | 25 | 25-120 |
| Creatinine, μmol/L | 84 | 74-120 |
| Creatinine kinase, U/L | 114 | 15-175 |
| γ-glutamyl transferase, U/L | 17 | 15-70 |
| Aspartate aminotransferase, U/L | 29 | 15-45 |
| Alanine aminotransferase, U/L | 21 | 10-50 |
| Lactate dehydrogenase, U/L | 494 | 300-620 |
| Unconjugated bilirubin, μmol/L | 24 | 3-21 |
| Haptoglobin, g/L | < 0.1 | 0.3-2.0 |
| Specialized laboratory investigation | ||
| G6PD activity (U/g Hb) in erythrocytes | 0.8 | 7.1-11.5 |
| PK activity (U/g Hb) in erythrocytes | 7.2 | 6.9-14.5 |
| HK activity (U/g Hb) in erythrocytes | 1.12 | 1.0-1.6 |
| G6PD activity (U/g protein) in leukocytes | 530 | 815-877 |
| Calculated G6PD activity (U/g protein) in muscle cells* | 0.5 | 3-4.7 |
| Km for G6P (μmol/L) in leukocytes | 40 | 55-71 |
| Km for NADP (μmol/L) in leukocytes | 45 | 66-76 |
| Ki value for NADPH (μmol/L) in leukocytes | 153 | 142-159 |
| G6PD activity at pH (range, 6.5-9.0) and elevated temperature (39°C, mimicking increased body temperature) | Normal | Normal |
| Oxidative hemolysis | 1.5% | < 2% |
(y = 0.39x + 0.198).9