Biologic and clinical characteristics of the patients
| Characteristic . | Test cohort, N = 307 . | Validation cohort, N = 705 . | ||
|---|---|---|---|---|
| No. (%) . | Median time Dx to Tx, y . | No. (%) . | Median time Dx to Tx, y . | |
| ZAP-70 negative | 166 (54) | 9.1 | 331 (47) | 8.4 |
| ZAP-70 positive | 141 (46) | 2.9 | 374 (53) | 2.6 |
| M-IGHV | 143 (47) | 9.2 | 251 (36) | 8.6 |
| U-IGHV | 164 (53) | 3.4 | 454 (64) | 3.8 |
| CD38− | 207 (67) | 7.8 | 374 (53) | 5.7 |
| CD38+ | 100 (33) | 3.4 | 331 (47) | 4.0 |
| Characteristic . | Test cohort, N = 307 . | Validation cohort, N = 705 . | ||
|---|---|---|---|---|
| No. (%) . | Median time Dx to Tx, y . | No. (%) . | Median time Dx to Tx, y . | |
| ZAP-70 negative | 166 (54) | 9.1 | 331 (47) | 8.4 |
| ZAP-70 positive | 141 (46) | 2.9 | 374 (53) | 2.6 |
| M-IGHV | 143 (47) | 9.2 | 251 (36) | 8.6 |
| U-IGHV | 164 (53) | 3.4 | 454 (64) | 3.8 |
| CD38− | 207 (67) | 7.8 | 374 (53) | 5.7 |
| CD38+ | 100 (33) | 3.4 | 331 (47) | 4.0 |
This table provides the data or number and percentage in parentheses (where appropriate) of patients with characteristics listed in the left column for the test cohort (middle columns) or validation cohort (right columns).
Dx indicates diagnosis; Tx, first treatment; M-IGHV, mutated IGHV; and U-IGHV, unmutated IGHV.