Table 4 Affection status by protein C... | American Society of Hematology

Table 4

Affection status by protein C deficiency and rs6589488 genotype

Protein C	rs6589488 genotype	Original kindred				Extended kindred
		Affected	Unaffected		Percent affected*	Affected	Unaffected		Percent affected*
		Affected	Age < 50 y	Age ≥ 50 y	Percent affected*	Affected	Age < 50 y	Age ≥ 50 y	Percent affected*
Normal	TT	3	139	38	7.32	3	162	38	7.32
Normal	AT	4	74	27	12.90	4	76	27	12.90
Normal	AA	0	9	2	0.00	0	9	2	0.00
Deficient	TT	2	23	11	15.38	6	37	27	18.18
Deficient	AT	19	17	3	86.36	25	22	4	86.21
Deficient	AA	2	4	1	66.67	2	4	1	66.67

Protein C	rs6589488 genotype	Original kindred				Extended kindred
		Affected	Unaffected		Percent affected*	Affected	Unaffected		Percent affected*
		Affected	Age < 50 y	Age ≥ 50 y	Percent affected*	Affected	Age < 50 y	Age ≥ 50 y	Percent affected*
Normal	TT	3	139	38	7.32	3	162	38	7.32
Normal	AT	4	74	27	12.90	4	76	27	12.90
Normal	AA	0	9	2	0.00	0	9	2	0.00
Deficient	TT	2	23	11	15.38	6	37	27	18.18
Deficient	AT	19	17	3	86.36	25	22	4	86.21
Deficient	AA	2	4	1	66.67	2	4	1	66.67

Including unaffected only if age ≥ 50 years.