Table 2 Interrelations of coagulation... | American Society of Hematology

Table 2

Interrelations of coagulation factors and venous thromboembolism risk factors among participants without venous thromboembolism: LITE

	Coagulation factor, %
	Factor IX	Factor X	Factor XI	Factor XII	Factor XIII
Continuous covariates (Spearman correlation coefficient)
FIX, %	1
FX, %	0.45‡	1
FXI, %	0.31‡	0.38‡	1
FXII, %	0.13‡	0.34‡	0.17‡	1
FXIII, %	0.22‡	0.24‡	0.22‡	0.13‡	1
Age, y	0.17‡	−0.09*	−0.14‡	−0.08*	0.09†
FVIII, %	0.19‡	0.03	0.12†	0.06	0.02
BMI, kg/m²	0.28‡	0.12‡	0.07*	−0.02	−0.04
D-dimer, μg/mL	0.14‡	0.003	0.03	−0.04	0.03
Binary covariates (coagulation factor means compared by Wilcoxon rank-sum test)
Sex, F/M	147/139‡	144/132‡	138/123‡	151/129‡	143/137*
Race, white/black	142/148*	138/140	131/134	147/125‡	139/145*
Study, ARIC/CHS	140/150‡	139/138	135/127‡	142/139	137/148‡
Diabetes, no/yes	142/157‡	139/139	130/144†	142/132*	140/142
Factor V Leiden, GG/AG or AA	144/143	138/140	132/138	142/139	141/138
Prothrombin 20210A, GG/AG	144/138	139/136	132/129	141/147	141/138

	Coagulation factor, %
	Factor IX	Factor X	Factor XI	Factor XII	Factor XIII
Continuous covariates (Spearman correlation coefficient)
FIX, %	1
FX, %	0.45‡	1
FXI, %	0.31‡	0.38‡	1
FXII, %	0.13‡	0.34‡	0.17‡	1
FXIII, %	0.22‡	0.24‡	0.22‡	0.13‡	1
Age, y	0.17‡	−0.09*	−0.14‡	−0.08*	0.09†
FVIII, %	0.19‡	0.03	0.12†	0.06	0.02
BMI, kg/m²	0.28‡	0.12‡	0.07*	−0.02	−0.04
D-dimer, μg/mL	0.14‡	0.003	0.03	−0.04	0.03
Binary covariates (coagulation factor means compared by Wilcoxon rank-sum test)
Sex, F/M	147/139‡	144/132‡	138/123‡	151/129‡	143/137*
Race, white/black	142/148*	138/140	131/134	147/125‡	139/145*
Study, ARIC/CHS	140/150‡	139/138	135/127‡	142/139	137/148‡
Diabetes, no/yes	142/157‡	139/139	130/144†	142/132*	140/142
Factor V Leiden, GG/AG or AA	144/143	138/140	132/138	142/139	141/138
Prothrombin 20210A, GG/AG	144/138	139/136	132/129	141/147	141/138

P ≤ .05.

P ≤ .005.

P < .001.