Summary of resistance to DAC in HL60D cells
| Group . | Selected resistant clones . | DAC resistance frequency . | Mutation . | ||
|---|---|---|---|---|---|
| LOH . | Deletion . | Frameshift . | |||
| HL6O | 0 | Undetected | 0 | 0 | 0 |
| HL6OD (pool) | 11 | 1.2 × 10−4 | 3 | 8 | 0 |
| HL6OD (clone) | 9 | 1.2 × 10−5 | 7 | 0 | 2 |
| Group . | Selected resistant clones . | DAC resistance frequency . | Mutation . | ||
|---|---|---|---|---|---|
| LOH . | Deletion . | Frameshift . | |||
| HL6O | 0 | Undetected | 0 | 0 | 0 |
| HL6OD (pool) | 11 | 1.2 × 10−4 | 3 | 8 | 0 |
| HL6OD (clone) | 9 | 1.2 × 10−5 | 7 | 0 | 2 |