Table 1

Characteristics of p210BCR/ABL/BHX2 mice with lymphoid leukemias

Mouse no.Age at disease, moPB parameters
Macroscopic tumor sitesSurface markersDiagnosis
WBC, ×109/LHb, g/LPlt, ×109/L
30 2.6 11.2 (blast ∼ 70%) 140 452 Spl, LN Thy1.2, CD19+, Gr.1, Mac1 B-cell leukemia 
3.0 10.0 (blast ∼ 60%) 124 238 Thy, Spl Thy1.2+, CD19, Gr.1, Mac1 T-cell leukemia 
17 4.2 82.4 (blast ∼ 100%) 109 525 Spl, LN Thy1.2+, CD19, Gr.1, Mac1 B-cell leukemia 
4.8 22.0 (blast ∼ 100%) 123 339 Thy, Spl, LN Thy1.2, CD19+, Gr.1, Mac1 T-cell leukemia 
18 5.2 68.0 (blast ∼ 100%) 118 345 Spl, LN Thy1.2, CD19+, Gr.1, Mac1 B-cell leukemia 
23 5.4 19.8 (blast ∼ 100%) 107 338 Spl, LN Thy1.2, CD19+, Gr.1, Mac1 B-cell leukemia 
Mouse no.Age at disease, moPB parameters
Macroscopic tumor sitesSurface markersDiagnosis
WBC, ×109/LHb, g/LPlt, ×109/L
30 2.6 11.2 (blast ∼ 70%) 140 452 Spl, LN Thy1.2, CD19+, Gr.1, Mac1 B-cell leukemia 
3.0 10.0 (blast ∼ 60%) 124 238 Thy, Spl Thy1.2+, CD19, Gr.1, Mac1 T-cell leukemia 
17 4.2 82.4 (blast ∼ 100%) 109 525 Spl, LN Thy1.2+, CD19, Gr.1, Mac1 B-cell leukemia 
4.8 22.0 (blast ∼ 100%) 123 339 Thy, Spl, LN Thy1.2, CD19+, Gr.1, Mac1 T-cell leukemia 
18 5.2 68.0 (blast ∼ 100%) 118 345 Spl, LN Thy1.2, CD19+, Gr.1, Mac1 B-cell leukemia 
23 5.4 19.8 (blast ∼ 100%) 107 338 Spl, LN Thy1.2, CD19+, Gr.1, Mac1 B-cell leukemia 

Spl indicates spleen; LN, lymph node; and Thy, thymus.

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