Enumeration of EBV-infected B cell subsets producing BZLF1, gp350, or EBV DNA
| B-cell subsets . | EBV healthy carriers . | |||
|---|---|---|---|---|
| 1 . | 2 . | 3 . | 4 . | |
| IgM memory B cells | ||||
| BZLF1-SCs/107 B cells | 17 | 7 | 6 | 6 |
| gp350-SCs/107 B cells | ND | ND | 3 | ND |
| EBV DNA copies/107 B cells* | ND | 36 | 1940 | ND |
| Memory B cells | ||||
| BZLF1-SCs/107 B cells | 143 | 156 | 407 | 51 |
| gp350 SCs/107 B cells | 20 | 10 | 30 | 10 |
| EBV DNA copies/107 B cells* | 353 | ND | 23100 | ND |
| B-cell subsets . | EBV healthy carriers . | |||
|---|---|---|---|---|
| 1 . | 2 . | 3 . | 4 . | |
| IgM memory B cells | ||||
| BZLF1-SCs/107 B cells | 17 | 7 | 6 | 6 |
| gp350-SCs/107 B cells | ND | ND | 3 | ND |
| EBV DNA copies/107 B cells* | ND | 36 | 1940 | ND |
| Memory B cells | ||||
| BZLF1-SCs/107 B cells | 143 | 156 | 407 | 51 |
| gp350 SCs/107 B cells | 20 | 10 | 30 | 10 |
| EBV DNA copies/107 B cells* | 353 | ND | 23100 | ND |
SCs indicates secreting cells; and ND, not detected.
EBV DNA copies were quantified in culture supernatants of circulating B cells of each subset.