Table 3 Relationship between acute... | American Society of Hematology

Table 3

Relationship between acute graft-versus-host disease and outcome in patients who achieved remission on protocol and went on to receive an HSCT in first remission

	GVHD		OR* (95% CI), log rank P
	Yes	No	OR* (95% CI), log rank P
No. of patients	44	20
Relapses	10	12
Deaths in remission (TRM)	17	3
Any event	27	15
Actuarial risk of relapse at 5 y (95% CI)	32% (15%-49%)	65% (43%-87%)	3.63 (1.44-9.18), .01†
Actuarial risk of TRM at 5 y (95% CI)	43% (27%-59%)	14% (0%-32%)	0.51 (0.19-1.34), > 0.1
Actuarial risk of any event at 5 y (95% CI)	62% (47%-76%)	70% (50%-90%)	1.42 (0.73-2.78), > 0.1

	GVHD		OR* (95% CI), log rank P
	Yes	No	OR* (95% CI), log rank P
No. of patients	44	20
Relapses	10	12
Deaths in remission (TRM)	17	3
Any event	27	15
Actuarial risk of relapse at 5 y (95% CI)	32% (15%-49%)	65% (43%-87%)	3.63 (1.44-9.18), .01†
Actuarial risk of TRM at 5 y (95% CI)	43% (27%-59%)	14% (0%-32%)	0.51 (0.19-1.34), > 0.1
Actuarial risk of any event at 5 y (95% CI)	62% (47%-76%)	70% (50%-90%)	1.42 (0.73-2.78), > 0.1

OR indicates odds ratio; and CI, confidence interval.

OR greater than 1 indicates an increased risk of the observed event in the absence of GVHD.

†

Statistically significant P values.

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