Table 1

2008 WHO classification of 100 patients with AML

Type and descriptionNo. of cases
AML with recurrent genetic abnormalities 10 
    AML with t(8;21)(q22;q22);(RUNX1-RUNX1T1
    AML with inv(16)(p13.1q22) or t(16;16)(p13.1;q22);(CBFB-MYH11
    APL with t(15;17)(q22;q12);(PML-RARA
    AML with t(9;11)(p22;q23);(MLLT3-MLL
    AML with t(6;9)(p23;q34);(DEK-NUP214
    AML with inv(3)(q21q26.2) or t(3;3)(q21;q26.2);(RPN1-EVI1
    AML (megakaryoblastic) with t(1;22)(p13;q13);(RBM15-MKL1
    Provisional entity: AML with mutated NPM1 26* 
    Provisional entity: AML with mutated CEBPA 9* 
AML with myelodysplasia-related changes 48 
    Prior history of myelodysplastic syndrome (MDS) 16 
    MDS-related cytogenetic abnormality 14 
    Multilineage dysplasia 41 
Therapy-related myeloid neoplasms 
Acute myeloid leukemia, not otherwise specified 39 
    AML with minimal differentiation 
    AML without maturation 
    AML with maturation 
    Acute myelomonocytic leukemia 
    Acute monoblastic/monocytic leukemia 
    Acute erythroid leukemia 
    Acute megakaryoblastic leukemia 
    Acute basophilic leukemia 
    Acute panmyelosis with myelofibrosis 
Type and descriptionNo. of cases
AML with recurrent genetic abnormalities 10 
    AML with t(8;21)(q22;q22);(RUNX1-RUNX1T1
    AML with inv(16)(p13.1q22) or t(16;16)(p13.1;q22);(CBFB-MYH11
    APL with t(15;17)(q22;q12);(PML-RARA
    AML with t(9;11)(p22;q23);(MLLT3-MLL
    AML with t(6;9)(p23;q34);(DEK-NUP214
    AML with inv(3)(q21q26.2) or t(3;3)(q21;q26.2);(RPN1-EVI1
    AML (megakaryoblastic) with t(1;22)(p13;q13);(RBM15-MKL1
    Provisional entity: AML with mutated NPM1 26* 
    Provisional entity: AML with mutated CEBPA 9* 
AML with myelodysplasia-related changes 48 
    Prior history of myelodysplastic syndrome (MDS) 16 
    MDS-related cytogenetic abnormality 14 
    Multilineage dysplasia 41 
Therapy-related myeloid neoplasms 
Acute myeloid leukemia, not otherwise specified 39 
    AML with minimal differentiation 
    AML without maturation 
    AML with maturation 
    Acute myelomonocytic leukemia 
    Acute monoblastic/monocytic leukemia 
    Acute erythroid leukemia 
    Acute megakaryoblastic leukemia 
    Acute basophilic leukemia 
    Acute panmyelosis with myelofibrosis 
*

The provisional entities were classified in other relevant categories.

or Create an Account

Close Modal
Close Modal