Summary of the additive regression models (stepwise method): predictor contribution to therapeutic dose of acenocoumarol and INR value at third day
| . | R2 . | P . | β coefficient (P) . | 
|---|---|---|---|
| Acenocoumarol dose | |||
| VKORC1 | 0.12 | .001 | −0.349 (.001) | 
| VKORC1 plus CYP4F2 | 0.19 | < .001 | −0.334 (.001); 0.229 (.018) | 
| INR at day 3 | |||
| VKORC1 | 0.08 | .007 | 0.286 (.007) | 
| VKORC1 plus CYP4F2 | 0.14 | .001 | 0.271 (.007); −0.283 (.005) | 
| . | R2 . | P . | β coefficient (P) . | 
|---|---|---|---|
| Acenocoumarol dose | |||
| VKORC1 | 0.12 | .001 | −0.349 (.001) | 
| VKORC1 plus CYP4F2 | 0.19 | < .001 | −0.334 (.001); 0.229 (.018) | 
| INR at day 3 | |||
| VKORC1 | 0.08 | .007 | 0.286 (.007) | 
| VKORC1 plus CYP4F2 | 0.14 | .001 | 0.271 (.007); −0.283 (.005) | 
INR indicates international normalized ratio.