Comparison of 14-day versus 21-day tipifarnib administration
. | 14 days (A) . | 21 days (B) . | P . |
---|---|---|---|
Toxicity, no. (%) of patients | |||
Grade 3 mucositis | 2/54 (4) | 4/30 (13) | .18 |
Induction death | 3/54 (6) | 6/30 (20) | .06 |
Efficacy, day to begin cycle 2, median (range) | 30 (29-43) | 35 (29-46) | |
Complete remission, no. (%) of patients | 16/54 (30) | 5/30 (17) | .29 |
. | 14 days (A) . | 21 days (B) . | P . |
---|---|---|---|
Toxicity, no. (%) of patients | |||
Grade 3 mucositis | 2/54 (4) | 4/30 (13) | .18 |
Induction death | 3/54 (6) | 6/30 (20) | .06 |
Efficacy, day to begin cycle 2, median (range) | 30 (29-43) | 35 (29-46) | |
Complete remission, no. (%) of patients | 16/54 (30) | 5/30 (17) | .29 |