Table 5

Comparison of 14-day versus 21-day tipifarnib administration

14 days (A)21 days (B)P
Toxicity, no. (%) of patients    
    Grade 3 mucositis 2/54 (4) 4/30 (13) .18 
    Induction death 3/54 (6) 6/30 (20) .06 
Efficacy, day to begin cycle 2, median (range) 30 (29-43) 35 (29-46)  
Complete remission, no. (%) of patients 16/54 (30) 5/30 (17) .29 
14 days (A)21 days (B)P
Toxicity, no. (%) of patients    
    Grade 3 mucositis 2/54 (4) 4/30 (13) .18 
    Induction death 3/54 (6) 6/30 (20) .06 
Efficacy, day to begin cycle 2, median (range) 30 (29-43) 35 (29-46)  
Complete remission, no. (%) of patients 16/54 (30) 5/30 (17) .29 
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